- Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression
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Zhang X, Deng QH, Deng JH, Wang SJ, Chen Q
- KMID: 2471035
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):137-147.
- doi: 10.4196/kjpp.2020.24.2.137
Ulcerative colitis (UC) is associated with intestinal immune imbalance and inflammatory response. Because dehydrolovastatin (DLVT), a derivative of lovastatin, has been recently shown to inhibit inflammation and relieve immune arthritis... -
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- An Atypical Extraintestinal Manifestation in a Child with Ulcerative Colitis: Cutaneous Leukocytoclastic Vasculitis
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Oh SJ, Choi Y, Kim CR, Park JH, Lee JH, Lee DY
- KMID: 2467210
- Ann Dermatol.
- 2020 Feb;32(1):90-91.
- doi: 10.5021/ad.2020.32.1.90
No abstract available. -
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- Effect of Sodium Cromoglycate on Acetic Acid-induced Ulcerative Colitis in Mice
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Ghafouri Z, Seyyedian , Nikbakht J, Kouhsari E, Bayat S, Zargar H, Houshmand
- KMID: 2471138
- Korean J Gastroenterol.
- 2020 Jan;75(1):39-45.
- doi: 10.4166/kjg.2020.75.1.39
BACKGROUND/AIMS: Ulcerative colitis (UC) is a type of inflammatory bowel disease that mainly involves the colon. Thus far, glucocorticoids and amino-salicylate have been the main treatment. METHODS: To assess drugs with... -
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- Comparison of Real-World Outcomes of Infliximab versus Adalimumab in Biologic-Naïve Korean Patients with Ulcerative Colitis: A Population-Based Study
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Han M, Jung YS, Cheon JH, Park S
- KMID: 2466335
- Yonsei Med J.
- 2020 Jan;61(1):48-55.
- doi: 10.3349/ymj.2020.61.1.48
PURPOSE: Data on the comparative effectiveness of infliximab (IFX) or adalimumab (ADA) in patients with ulcerative colitis (UC) are extremely limited, especially in the Asian population. We compared clinically important... -
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- Polypharmacy is a risk factor for disease flare in adult patients with ulcerative colitis: a retrospective cohort study
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Wang J, Nakamura T, Tuskey AG, Behm BW
- KMID: 2465815
- Intest Res.
- 2019 Oct;17(4):496-503.
- doi: 10.5217/ir.2019.00050
BACKGROUND/AIMS: Polypharmacy is a common clinical problem with chronic diseases that can be associated with adverse patient outcomes. The present study aimed to determine the prevalence and patient-specific characteristics associated... -
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- Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan
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Yanagi T, Ushijima K, Koga H, Tomomasa T, Tajiri H, Kunisaki R, Isihige T, Yamada H, Arai K, Yoden A, Aomatsu T, Nagata S, Uchida K, Ohtsuka Y, Shimizu T
- KMID: 2465813
- Intest Res.
- 2019 Oct;17(4):476-485.
- doi: 10.5217/ir.2019.00027
BACKGROUND/AIMS: Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance... -
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- Tacrolimus in pediatric ulcerative colitis: does it have a role?
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Kim S
- KMID: 2465809
- Intest Res.
- 2019 Oct;17(4):441-442.
- doi: 10.5217/ir.2019.00124
No abstract available. -
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- A Case of Anti-Le(bH) Antibody Identified in a Patient with Ulcerative Colitis
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Hong J, Kim MS, Kim JS, Park H, Ko DH, Hwang SH, Oh HB
- KMID: 2458688
- Lab Med Online.
- 2019 Oct;9(4):254-257.
- doi: 10.3343/lmo.2019.9.4.254
A 67-year-old man previously diagnosed with ulcerative colitis complained of difficulty in defecation and underwent balloon dilatation of rectum, but the procedure failed. The patient was transferred to a surgical... -
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- Diffuse Involvement of Primary Colorectal Lymphoma Simulating Ulcerative Colitis
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Kim JY, Chang SH, Kim HS, Joo M
- KMID: 2459582
- J Pathol Transl Med.
- 2019 Sep;53(5):332-336.
- doi: 10.4132/jptm.2019.07.12
Diffuse involvement of colorectal lymphoma masquerading as colitis is a very rare presentation of primary colorectal lymphoma. Detecting occult lymphoma is difficult in the setting of diffuse colonic involvement with... -
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- Multidrug-resistant Disseminated Tuberculosis Related to Infliximab in a Patient with Ulcerative Colitis and Negative Evaluation for Latent Tuberculosis
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Jun YK, Chun J, Kang EA, Lee HJ, Im JP, Kim JS
- KMID: 2458698
- Korean J Gastroenterol.
- 2019 Sep;74(3):168-174.
- doi: 10.4166/kjg.2019.74.3.168
Anti-tumor necrosis factor (anti-TNF) is an effective biological agent for the treatment of moderate-to-severe active ulcerative colitis (UC) refractory to conventional therapy. On the other hand, anti-TNF therapy is strongly... -
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- Efficacy and safety of abrilumab, an α4β7 integrin inhibitor, in Japanese patients with moderate-to-severe ulcerative colitis: a phase II study
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Hibi T, Motoya S, Ashida T, Sai S, Sameshima , Nakamura S, Maemoto A, Nii M, Sullivan B, Gasser Jr , Suzuki Y
- KMID: 2454746
- Intest Res.
- 2019 Jul;17(3):375-386.
- doi: 10.5217/ir.2018.00141
BACKGROUND/AIMS: Inhibition of α4β7 integrin has been shown to be effective for induction and maintenance therapy in patients with ulcerative colitis (UC). We investigated the effects of varying doses of... -
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- Real-time data monitoring for ulcerative colitis: patient perception and qualitative analysis
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Walsh A, Matini L, Hinds C, Sexton V, Brain O, Keshav S, Geddes J, Goodwin G, Collins G, Travis S, Peters M
- KMID: 2454745
- Intest Res.
- 2019 Jul;17(3):365-374.
- doi: 10.5217/ir.2018.00173
BACKGROUND/AIMS: TrueColours ulcerative colitis (TCUC) is a comprehensive web-based program that functions through email, providing direct links to questionnaires. Several similar programs are available, however patient perspectives are unexplored. METHODS: A... -
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- Adherence to Asacol once daily versus divided regimen for maintenance therapy in ulcerative colitis: a prospective, multicenter, randomized study
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Park SK, Park SH, Eun CS, Seo GS, Im JP, Kim TO, Park DI
- KMID: 2454743
- Intest Res.
- 2019 Jul;17(3):349-356.
- doi: 10.5217/ir.2018.00064
BACKGROUND/AIMS: A once-daily (OD) regimen of 5-aminosalicylic acid (5-ASA) was easier to comply with than a divided daily (DD) regimen, and that treatment efficacy for ulcerative colitis (UC) was not... -
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- Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia
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Ooi CJ, Hilmi I, Banerjee R, Chuah SW, Ng SC, Wei SC, Makharia G, Pisespongsa P, Chen MH, Ran ZH, Ye BD, Park DI, Ling KL, Ong D, Ahuja V, Goh KL, Sollano J, Lim WC, Leung WK, Ali RA, Wu DC, Ong E, Mustaffa N, Limsrivilai J, Hisamatsu , Yang SK, Ouyang Q, Geary R, De Silva J, Rerknimitr R, Simadibrata M, Abdullah M, Leong RW, on behalf of the Asia Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease and Asian Organization for Crohn's and Colitis
- KMID: 2454738
- Intest Res.
- 2019 Jul;17(3):285-310.
- doi: 10.5217/ir.2019.00026
The Asia-Pacific Working Group on inflammatory bowel disease (IBD) was established in Cebu, Philippines, under the auspices of the Asian Pacific Association of Gastroenterology with the goal of improving IBD... -
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- Subcutaneous integrin inhibitors may provide more treatment options for patients with moderate-to-severe ulcerative colitis
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Yoon H
- KMID: 2454737
- Intest Res.
- 2019 Jul;17(3):283-284.
- doi: 10.5217/ir.2019.00070
No abstract available. -
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- The Role of Mucus Barrier in Ulcerative Colitis Pathogenesis Using Proteomics
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Lee CM
- KMID: 2447603
- Korean J Gastroenterol.
- 2019 May;73(5):311-312.
- doi: 10.4166/kjg.2019.73.5.311
No abstract available. -
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- Remission of diffuse ulcerative duodenitis in a patient with ulcerative colitis after infliximab therapy: a case study and review of the literature
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Choi YS, Kim JK, Kim WJ, Kim MJ
- KMID: 2449969
- Intest Res.
- 2019 Apr;17(2):273-277.
- doi: 10.5217/ir.2018.00122
Although ulcerative colitis (UC) is confined to colonic and rectal mucosa in a continuous fashion, recent studies have also demonstrated the involvement of upper gastrointestinal tract as diagnostic endoscopy becomes... -
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- Individualized treatment based on CYP3A5 single-nucleotide polymorphisms with tacrolimus in ulcerative colitis
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Okabayashi S, Kobayashi , Saito E, Toyonaga T, Ozaki R, Sagami S, Nakano M, Tanaka J, Yagisawa K, Kuronuma S, Takeuchi O, Hibi T
- KMID: 2449963
- Intest Res.
- 2019 Apr;17(2):218-226.
- doi: 10.5217/ir.2018.00117
BACKGROUND/AIMS: The pharmacokinetics of tacrolimus (TAC) is known to be largely influenced by single-nucleotide polymorphisms (SNPs) in CYP3A5. Patients starting TAC require careful dose adjustment, owing to the wide range... -
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- Recurrent Eosinophilic Pneumonia Associated with Mesalazine Suppository in a Patient with Ulcerative Colitis
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Park M, Lee J, Kang SB, Park Y
- KMID: 2443636
- Korean J Gastroenterol.
- 2019 Apr;73(4):225-229.
- doi: 10.4166/kjg.2019.73.4.225
Mesalazine suppositories are widely used to treat ulcerative colitis and have a guaranteed safety profile, but although rare, they can cause pulmonary toxicity. A 35-year-old woman with ulcerative colitis was... -
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- Randomized, crossover questionnaire survey of acceptabilities of controlled-release mesalazine tablets and granules in ulcerative colitis patients
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Yagisawa K, Kobayashi , Ozaki R, Okabayashi S, Toyonaga T, Miura M, Hayashida , Saito E, Nakano M, Matsubara , Hisamatsu , Hibi T
- KMID: 2438447
- Intest Res.
- 2019 Jan;17(1):87-93.
- doi: 10.5217/ir.2018.00078
BACKGROUND/AIMS: Oral mesalazine is an important treatment for ulcerative colitis (UC), and non-adherence to mesalazine increases the risk of relapse. Controlled-release (CR) mesalazine has 2 formulations: tablets and granules. The... -
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