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Ann Dermatol.  2006 Jun;18(1):14-17. 10.5021/ad.2006.18.1.14.

Treatment of Keratoacanthoma with 5% Imiquimod Cream

Affiliations
  • 1Department of Dermatology, Korea University Ansan Hospital, Kyunggido, Korea. kumcihk @unitel.co.kr

Abstract

Keratoacanthoma is a rapidly growing tumor that histologically resembles squamous cell carcinoma. Surgical excision is a desirable therapeutic option, but several other treatment modalities are available. We report on two cases of keratoacanthoma that were treated with imiquimod 5% cream. Imiquimod was applied daily for the first 6 or 7 days, and then reduced to alternate days according to the tolerance and erythema severity of the patient. In both patients, the tumors fully regressed after five weeks of treatment.

Keyword

Imiquimod 5% cream; Keratoacanthoma

MeSH Terms

Carcinoma, Squamous Cell
Erythema
Humans
Keratoacanthoma*
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