Ann Dermatol.  2011 Feb;23(1):98-100. 10.5021/ad.2011.23.1.98.

Warty Dyskeratoma Involving Two Adjoining Follicles

Affiliations
  • 1Department of Dermatology, School of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea. tyyoon@chungbuk.ac.kr
  • 2Department of Internal Medicine, School of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea.

Abstract

Warty dyskeratoma (WD) is a rare epidermal tumor that frequently arises as a papule or nodule on the head or neck of middle-aged or older persons. Histologically, it shows a cup-shaped keratin-filled invagination of an acanthotic epidermis, suprabasilar clefting with villi projecting into the clefts and acantholytic dyskeratotic cells are also present. The changes almost always involve a single hair follicle. We describe a distinctive case of WD that showed involvement of two adjoining follicles within a solitary lesion.

Keyword

Multiple follicles; Warty dyskeratoma

MeSH Terms

Epidermis
Hair Follicle
Head
Humans
Neck

Figure

  • Fig. 1 A solitary, well-defined, erythematous, hairless nodule with a hyperkeratotic plug on the left parietal scalp.

  • Fig. 2 (A) Two large cup-shaped invaginations containing keratinous material (H&E, ×40). (B) The lower portion of each invagination shows suprabasal clefts and villi with acantholytic dyskeratotic cells. Typical corps ronds in the granular layer and a moderate inflammatory infiltrate consisting of lymphocytes and histiocytes in the dermis are observed (H&E, ×100).


Reference

1. Graham JH, Helwig EB. Isolated dyskeratosis follicularis. AMA Arch Derm. 1958. 77:377–389.
Article
2. Szymanski FJ. Warty dyskeratoma; a benign cutaneous tumor resembling Darier's disease microscopically. AMA Arch Derm. 1957. 75:567–572.
3. Tanay A, Mehregan AH. Warty dyskeratoma. Dermatologica. 1969. 138:155–164.
Article
4. Chon HJ, Hong SJ, Kang H, Son SJ. A case of warty dyskeratoma. Korean J Dermatol. 1999. 37:694–696.
5. Griffiths TW, Hashimoto K, Sharata HH, Ellis CN. Multiple warty dyskeratomas of the scalp. Clin Exp Dermatol. 1997. 22:189–191.
Article
6. Koç M, Kavala M, Kocatürk E, Mete O, Can B, Zindanci I, et al. Multiple warty dyskeratomas on the scalp. Dermatol Online J. 2009. 15:8.
Article
7. Gorlin RJ, Peterson WC Jr. Warty dyskeratoma. A note concerning its occurrence on the oral mucosa. Arch Dermatol. 1967. 95:292–293.
Article
8. Duray PH, Merino MJ, Axiotis C. Warty dyskeratoma of the vulva. Int J Gynecol Pathol. 1983. 2:286–293.
9. Lee IJ, Hur W, Ahn SK, Lee WS, Kim SC, Lee SH. Three cases of warty dyskeratoma. Korean J Dermatol. 1992. 30:564–568.
10. Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L. Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm. J Am Acad Dermatol. 2002. 47:423–428.
Article
11. Azuma Y, Matsukawa A. Warty dyskeratoma with multiple lesions. J Dermatol. 1993. 20:374–377.
Article
12. Abramovits W, Abdelmalek N. Treatment of warty dyskeratoma with tazarotenic acid. J Am Acad Dermatol. 2002. 46:S4.
Article
Full Text Links
  • AD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr