Cancer Res Treat.  2009 Mar;41(1):50-52.

Herpes Zoster Duplex Bilateralis in a Patient with Breast Cancer

Affiliations
  • 1Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea. Beomjoon@unitel.co.kr
  • 2Department of Pathology, College of Medicine, Chung-Ang University, Seoul, Korea.

Abstract

The skin lesion of herpes zoster is classically limited to a single dermatome, and most cases of multi-dermatomal herpes zoster have contiguous skin lesions. Noncontigous multi-dermatomal herpes zoster is very rare in both immunocompetent and immunosuppressed persons. The phenomenon of zoster occurring in two non-contiguous dermatomes has been referred to as zoster duplex unilateralis or bilateralis. We report here on a case of herpes zoster duplex bilateralis in a 49-year-old woman who had previously received chemotherapy for breast cancer treatment.

Keyword

Herpes zoster; Breast neoplasms

MeSH Terms

Breast
Breast Neoplasms
Female
Herpes Zoster
Humans
Middle Aged
Skin

Figure

  • Fig. 1 The grouped erythematous vesicles on the left anterior chest (Lt. T4) and both upper back areas (Rt. T4).

  • Fig. 2 Intraepidermal blisters with ballooning degeneration, reticular degeneration, characteristic intranuclear inclusion bodies and acantholytic multinucleated giant cells (H&E, A:×100, B:×200).

  • Fig. 3 PCR (Polymerase chain reaction) for varicella-zoster virus showing a positive band of 208 bp.


Reference

1. Straus SE, Schmader KE, Oxman MN. Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editors. Varicella and herpes zoster. Dermatology in general medicine. 2003. 6th ed. New York: McGrow-Hill;p. 2070–2085.
2. Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ. Neurologic complications of the reactivation of varicella-zoster virus. N Engl J Med. 2000; 342:635–645. PMID: 10699164.
Article
3. Odom RB, James WD, Berger TG. Viral diseases. Andrews' diseases of the skin. 2000. 9th ed. Philadelphia: W.B. Saunders Co.;p. 486–491.
4. Vu AQ, Radonich MA, Heald PW. Herpes zoster in seven disparate dermatomes (zoster multiplex): Report of a case and review of the literature. J Am Acad Dermatol. 1999; 40:868–869. PMID: 10321638.
Article
5. Arvin AM. Varicella-zoster virus. Clin Microbiol Rev. 1996; 9:361–381. PMID: 8809466.
Article
6. Takayama N, Yamada H, Kaku H, Minamitami M. Herpes zoster in immunocompetent and immunocompromised Japanese children. Pediatr Int. 2000; 42:275–279. PMID: 10881585.
Article
7. Peretz A, Nowatzky J, Steiner I. Neurological picture: Herpes zoster duplex bilateralis. J Neurol Neurosurg Psychiatry. 2007; 78:818. PMID: 17635977.
Full Text Links
  • CRT
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr