Clin Endosc.  2014 Jan;47(1):115-118.

Extramedullary Plasmacytoma of the Pancreas Diagnosed Using Endoscopic Ultrasonography-Guided Fine Needle Aspiration

• Roh YH
• Hwang SY
• Lee SM
• Im JW
• Kim JS
• Kwon KA
• Song JY
• Jeong SY

Abstract

Extramedullary plasmacytoma involves organs outside the bone marrow; however, involvement of the pancreas is rare. We recently experienced a case of extramedullary plasmacytoma of the pancreas that was diagnosed by endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA). EUS-FNA, which has a high diagnostic accuracy and an excellent safety profile, is the modality of choice for establishing tissue diagnosis. We report a case of extramedullary plasmacytoma of the pancreas diagnosed using EUS-FNA.

Keyword

Extramedullary plasmacytoma; Pancreas; Endosonography; Biopsy, fine-needle

MeSH Terms

Biopsy, Fine-Needle*
Bone Marrow
Diagnosis
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Endosonography
Pancreas*
Plasmacytoma*

Figure

• 

  Fig. 1 Pelvic magnetic resonance imaging shows a large bone destructive mass with a soft tissue mass in the right inferior pelvic bone (arrow).

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  Fig. 2 Contrast-enhanced abdomen-pelvis computed tomography shows a suspicious ill-defined marginated mass in the body of the pancreas (arrow).

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  Fig. 3 T2-weighted magnetic resonance imaging with a diffusion weighted image shows that the pancreatic proximal body contains (A) a mass of subtle high signal intensity with (B) marked diffusion restriction (arrows).

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  Fig. 4 (A) Endoscopic ultrasound shows a hypoechoic and heterogenous mass in the body of the pancreas. (B) Fine needle aspiration was performed and samples were obtained for pathological analysis.

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  Fig. 5 Endoscopic ultrasonography-guided fine needle aspiration cytology (×400) shows (A) a predominantly monomorphic population of plasma cells with (B) positivity for CD138.

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