Brain Neurorehabil.  2015 Sep;8(2):109-112. 10.12786/bn.2015.8.2.109.

Toluene-induced Encephalopathy: A Case Report

  • 1Department of Rehabilitation Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Korea.


Toluene is one of well-known neuro-toxicants. It can readily cross the blood-brain-barrier and mainly affect the central nervous system (CNS). An inhalation is the typical route of its human exposure and show a variety of symptoms involving cerebral and cerebellar dysfunction, bronchial asthma, chemical pneumonitis, toxic hepatitis, renal tubular acidosis, intestinal obstruction, and myelo-dysplastic syndrome. In this case, toluene-inhalated showed numerous CNS and systemic symptoms. Authors performed such gait analysis, gross and fine motor evaluations, computerized neurocognitive test that we noticed the impaired results. After comprehensive rehabilitation for four weeks, patient improved as much as she could carry out the independent life, and finally discharged home. Authors report the case of toluene-induced encephalopathy in Republic of Korea for the first time.


toluene; encephalopathy; neurotoxin
Full Text Links
  • BN
  • Twitter
  • Facebook
Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: