Neonatal Med.  2016 May;23(2):121-126. 10.5385/nm.2016.23.2.121.

Enoxaparin Therapy for Arterial Thrombosis After Umbilical Cord Catheterization in Preterm Infants

• Kim YJ
• Kim YD
• Choi JH

• KMID: 2164927
• DOI: http://doi.org/10.5385/nm.2016.23.2.121

Abstract

The incidence of symptomatic thrombosis of umbilical arterial catheterization is 1-3%. Therapeutic options may include: using heparin or low molecular weight heparin, using a thrombolytic agent, or surgical thrombectomy. However, there are insufficient data to recommend any one treatment over the others. Recently, enoxaparin, a low molecular weight heparin, has emerged as a drug of choice for the treatment of neonatal thrombosis due to pharmacologic stability over unfractionated heparin or thrombolytic agents. We report a case of successful treatment of aortic thrombosis after umbilical arterial catheterization with enoxaparin in preterm infants.

Keyword

Preterm infants; Enoxaparin; Arterial thrombosis; Umbilical artery catheter

MeSH Terms

Catheterization*
Catheters*
Enoxaparin*
Fibrinolytic Agents
Heparin
Heparin, Low-Molecular-Weight
Humans
Incidence
Infant, Newborn
Infant, Premature*
Thrombectomy
Thrombosis*
Umbilical Cord*
Enoxaparin
Fibrinolytic Agents
Heparin
Heparin, Low-Molecular-Weight