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Management of antithrombotic agents and current issues in patients undergoing endoscopic submucosal dissection

Park CH

Postoperative bleeding is a common adverse event in endoscopic submucosal dissection (ESD) and may be life-threatening. Postoperative bleeding occurs frequently in patients treated with antithrombotic agents, including aspirin, antiplatelet agents,...
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When do we need more than local compression to control intraoral haemorrhage?

Sohn JB, Lee H, Han YS, Jung DU, Sim HY, Kim HS, Oh S

OBJECTIVES: The aims of this study were to determine the effectiveness of local compression in patients presenting to the emergency room with intraoral bleeding and to identify when complex haemostatic...
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Predictors of Hematoma Enlargement in Patients with Spontaneous Intracerebral Hemorrhage Treated with Rapid Administration of Antifibrinolytic Agents and Strict Conservative Management

Kim CH, Lee SW, Kim YH, Sung SK, Son DW, Song GS

OBJECTIVE: Spontaneous intracerebral hemorrhage (ICH) is caused by the rupture of small blood vessels and other health problems. In ICH patients, hematoma enlargement is the most critical risk factor for...
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Minimal Dose of Tranexamic Acid Is Effective in Reducing Blood Loss in Complex Spine Surgeries: A Randomized Double-Blind Placebo Controlled Study

Shakeri M, Salehpour , Shokouhi G, Aeinfar K, Aghazadeh , Mirzaei F, Alavi SA

STUDY DESIGN: A randomized double-blind placebo controlled study. PURPOSE: In the present study, we aimed to assess the efficacy of tranexamic acid (TXA) in reducing blood loss after laminectomy and posterolateral...
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Management of Patients on Antithrombotic Agents Undergoing Endoscopy

Kim JS, Kim BW

Antithrombotic agents are used increasingly in Asia. The management of patients on antithrombotics undergoing elective or emergency endoscopy has become an increasing clinical challenge for gastroenterologists. Current practice guidelines have...
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A Prospective Multicenter Study Evaluating Bleeding Risk after Endoscopic Ultrasound-Guided Fine Needle Aspiration in Patients Prescribed Antithrombotic Agents

Kawakubo K, Yane K, Eto K, Ishiwatari H, Ehira N, Haba S, Matsumoto , Shinada K, Yamato H, Kudo T, Onodera M, Okuda T, Taya-Abe Y, Kawahata S, Kubo K, Kubota Y, Kuwatani M, Kawakami H, Katanuma A, Ono M, Hayashi T, Uebayashi , Sakamoto N

BACKGROUND/AIMS: Although the risk of bleeding after endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is low, the safety of EUS-FNA in patients prescribed antithrom-botic agents is unclear. Therefore, this study evaluated...
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The Bleeding Risk after Endoscopic Ultrasound-Guided Fine Needle Aspiration in Patients Taking Antithrombotic Agents Is Not Negligible

Jang DK, Lee SH

No abstract available.
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Improper Use of Thrombolytic Agents in Acute Hemiparesis Following Misdiagnosis of Acute Ischemic Stroke

Kim MC, Kim SW

OBJECTIVE: Acute hemiparesis is often an early presentation of acute ischemic stroke, though it can occur in various disorders. This study aimed to investigate the improper use of thrombolytic agents...
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The Evolution of the Neurosurgical Treatment of Ischemic Stroke

Withrow J, Todnem N, Rahimi S

The neurosurgical approach to the management of ischemic stroke has evolved dramatically over the past century with the bulk of these changes occurring over the past 25 years. With recent...
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Infarct Core Expansion on Computed Tomography before and after Intravenous Thrombolysis

Song D, Yoo J, Baek JH, Kim J, Lee HS, Kim YD, Nam HS, Heo JH

PURPOSE: Infarct core can expand rapidly in acute stroke patients receiving intravenous tissue plasminogen activator (IV t-PA). We investigated changes in the extent of infarct core during IV t-PA treatment,...
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Focal Subarachnoid Hemorrhage Mimicking Recurrent Transient Ischemic Attack

Jeong BM, Ryu HU, Kang MK, Kang JJ, Seo MW, Oh SY, Shin BS

Focal subarachnoid hemorrhage occasionally presents as transient focal neurologic episodes mimicking transient ischemic attack (TIA). Unless properly diagnosed, it may aggravate cerebral hemorrhage by administering antithrombotic agents. Therefore, clinicians need...
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Medical Treatment of Intracranial Atherosclerosis: An Update

Kim JS, Bang OY

For patients with symptomatic intracranial atherosclerosis (ICAS), antithrombotic agents are the mainstay of therapy. Anticoagulation (warfarin) is not widely used since it is not more effective than aspirin and carries...
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Efficacy of Topical Tranexamic Acid in Treatment of Melasma

Yoo J, Ahn H, Kim MS, Jue MS, Choi KH

  • KMID: 2386238
  • Korean J Dermatol.
  • 2017 Jun;55(5):283-289.
BACKGROUND: Tranexamic acid (TXA), a plasmin inhibitor, has been used orally or via intradermal injection to treat melasma; however, there are limited studies regarding efficacy and safety of topical application...
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Prediction and Prevention of Postpolypectomy Bleeding: Necessity of a Different Approach for Patients Using Antithrombotic Agents

Kim DH

No abstract available.
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Top of the Basilar Syndrome after 2nd Cervical Spine Fracture

Kim SP, Sun KH, Kim SJ, Kim TH

Top of the basilar (TOB) syndrome occurs with occlusion of the rostral portion of the basilar artery that supplies blood to the midbrain, thalamus, and temporal and occipital lobes. Symptoms...
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Safety and Efficacy of Catheter Direct Thrombolysis in Management of Acute Iliofemoral Deep Vein Thrombosis: A Systematic Review

Elbasty A, Metcalf J

PURPOSE: Catheter direct thrombolysis (CDT) has been shown to be an effective treatment for deep venous thrombosis. The objective of the review is to improve safety and efficacy of the...
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Computed Tomography-Based Thrombus Imaging for the Prediction of Recanalization after Reperfusion Therapy in Stroke

Heo JH, Kim K, Yoo J, Kim YD, Nam HS, Kim EY

The prediction of successful recanalization following thrombolytic or endovascular treatment may be helpful to determine the strategy of recanalization treatment in acute stroke. Thrombus can be detected using noncontrast computed...
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Effectiveness and Safety of Tranexamic Acid in Spinal Deformity Surgery

Choi HY, Hyun SJ, Kim KJ, Jahng TA, Kim HJ

OBJECTIVE: Spinal deformity surgery has the potential risk of massive blood loss. To reduce surgical bleeding, the use of tranexamic acid (TXA) became popular in spinal surgery, recently. The purpose...
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Difference in the Location and Risk Factors of Cerebral Microbleeds According to Ischemic Stroke Subtypes

Kim BJ, Yoon Y, Sohn H, Kang DW, Kim JS, Kwon SU

BACKGROUND AND PURPOSE: The location of cerebral microbleeds (CMBs) may differ according to ischemic stroke subtype, and the underlying pathomechanism may differ by their location. Here, we investigated the characteristics...
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Management of Acute Submacular Hemorrhage with Intravitreal Injection of Tenecteplase, Anti-vascular Endothelial Growth Factor and Gas

Lee JP, Park JS, Kwon OW, You YS, Kim SH

PURPOSE: To evaluate the visual and anatomical outcomes for neovascular age-related macular degeneration with submacular hemorrhage after intravitreal injections of tenecteplase (TNK), anti-vascular endothelial growth factor (VEGF) and expansile gas. METHODS:...
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