Ann Dermatol.  2007 Mar;19(1):22-24. 10.5021/ad.2007.19.1.22.

Necrobiotic Xanthogranuloma with Multiple Myeloma and No Periorbital Involvement

• Yoon SY
• Park HJ
• Lee JY
• Cho BK

• KMID: 2156320
• DOI: http://doi.org/10.5021/ad.2007.19.1.22

Abstract

Necrobiotic xanthogranuloma (NXG) is a rare multisystemic disease that manifests as cutaneous inflammatory lesions and has a strong association with paraproteinemia and an increased risk of plasma cell dyscrasias and other lymphoproliferative disorders. Its general skin manifestation is multiple, asymptomatic, indurated nodules or plaques with a yellowish hue which frequently affect the periorbital regions. This case is unusual in that cutaneous lesions developed only at the extremities without periorbital involvement, accompanied by multiple myeloma.

Keyword

Multiple myeloma; Necrobiotic xanthogranuloma

MeSH Terms

Extremities
Lymphoproliferative Disorders
Multiple Myeloma*
Necrobiotic Xanthogranuloma*
Paraproteinemias
Skin Manifestations