Korean J Gastrointest Endosc.
2006 Oct;33(4):220-225.
A Case of Primary Malignant Melanoma of the Esophagus Treated by Esophagectomy
- Affiliations
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- 1Department of Gastroenterology, Ajou University of College of Medicine, Suwon, Korea. lkm5104@ajou.ac.kr
- 2Department of Thoracic and Cardiovascular Surgery, Ajou University of College of Medicine, Suwon, Korea.
- 3Department of Pathology, Ajou University of College of Medicine, Suwon, Korea.
Abstract
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A primary malignant melanoma of the esophagus is a very rare disease representing approximately 0.1~0.2% of all esophageal neoplasms and 0.5% of all mucosal melanomas. Despite a surgical resection, a primary malignant melanoma of the esophagus has a poor prognosis, mainly due to the fast development of hematogenous and lymphatic metastases. However, a resection of the tumor appears to be the treatment of choice. Local excision does not prolong the survival of patients. After a radical excision, the mean survival time is 7~12 months and the estimated 5 year survival is 4.2%. However, after a local excision, the average survival time is 9 months and there is no report of a patient who survived more than 1year. We encountered a 55-year-old woman with a primary malignant melanoma of the esophagus, who underwent a radical esophageal resection with a lymph node dissection. We report this case with a review of the relevant literature.