J Korean Diabetes.  2015 Jun;16(2):101-107. 10.4093/jkd.2015.16.2.101.

Diagnosis and Glycemic Control of Type 1 Diabetes

• Kim JH

• KMID: 2137267
• DOI: http://doi.org/10.4093/jkd.2015.16.2.101

Abstract

Type 1 diabetes mellitus (T1DM) is characterized by an immune-mediated beta-cell destruction that causes lifelong insulin dependency. Diagnosis of diabetes is based on fasting glucose, 2-h plasma glucose value after a 75-g oral glucose tolerance test, or hemoglobin A1c (HbA1c) levels. Differentiation between type 1 and 2 diabetes is important for both education and treatment. Diabetes-associated autoantibodies, c-peptide and clinical characteristics should be considered to confirm the diagnosis of T1DM. A single HbA1c target of < 7.5% across all pediatric age groups is recommended. In nonpregnant adults, a reasonable HbA1c goal is < 7.0% to reduce the incidence of microvascular complications of T1DM. Glycemic targets should be individualized according to lifestyle, psychosocial and medical circumstances.

Keyword

Diagnosis; Glycemic target; Type 1 diabetes

MeSH Terms

Adult
Autoantibodies
Blood Glucose
C-Peptide
Diabetes Mellitus, Type 1
Diagnosis*
Education
Fasting
Glucose
Glucose Tolerance Test
Humans
Incidence
Insulin
Life Style
Autoantibodies
C-Peptide
Glucose
Insulin

Reference

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