J Cardiovasc Ultrasound.  2011 Mar;19(1):45-49. 10.4250/jcu.2011.19.1.45.

Ovarian Tumor-Associated Carcinoid Heart Disease Presenting as Severe Tricuspid Regurgitation

• Shin HW
• Kim H
• Yoon HJ
• Park HS
• Cho YK
• Nam CW
• Hur SH
• Kim YN
• Kim KB

• KMID: 2135434
• DOI: http://doi.org/10.4250/jcu.2011.19.1.45

Abstract

Carcinoid heart disease is characterized by heart valve dysfunction as well as carcinoid symptomatology. We report a case of carcinoid heart disease associated with a primary ovarian tumor. A 60-year-old woman presented for dyspnea evaluation with a history of facial flushing, telangiectatic skin changes, and pitting edema of both lower extremities. Chest radiography showed cardiomegaly, and echocardiography revealed an isolated, severe tricuspid regurgitation without left-sided valvular dysfunction. The tricuspid leaflets were severely retracted and shortened, resulting in poor coaptation. Furthermore, mild pulmonary valve stenosis and moderate regurgitation were found along with this deformation. The 24-hour urine analysis revealed an increased level of 5-hydroxyindoleacetic acid, and an ovarian tumor was apparent on computed tomography images. The mass was surgically removed, and the patient was diagnosed as having a primary ovarian carcinoid tumor. She was treated with chemotherapy and regularly followed-up with supportive treatments, deferring surgical correction.

Keyword

Carcinoid; Tricuspid regurgitation; Echocardiography; Ovarian tumor

MeSH Terms

Carcinoid Heart Disease
Carcinoid Tumor
Cardiomegaly
Dyspnea
Echocardiography
Edema
Female
Flushing
Heart Valves
Humans
Lower Extremity
Middle Aged
Pulmonary Valve Stenosis
Skin
Thorax
Tricuspid Valve Insufficiency