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Surgical Ablation of Atrial Fibrillation in Patients Undergoing Bioprosthetic Valve Replacement

Pyo W, Park SJ, Kim WK, Kim HJ, Kim JB, Jung SH, Joo SJ, Chung CH, Lee JW

BACKGROUND: Scarce data have been reported on the efficacy of concomitant atrial fibrillation (AF) ablation in patients undergoing bioprosthetic valve replacement. METHODS: From 2001 and 2014, 146 consecutive patients (69.3±9.4 years,...
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Gross age-related changes and diseases in human heart valves

Gumpangseth T, Mahakkanukrauh P, Das S

Cardiac valves are highly complex structures optimizing their function during the cardiac cycle. They open and close directed by blood flow under different pressure conditions in the dynamic environment in...
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Symptom Clusters and Quality of Life Changes according to Recovery Period of Patients with Heart Valve Surgery

Hwang SJ, Kang JH

PURPOSE: It is widely accepted that addressing multiple symptoms together is the preferred approach in assessment and intervention and results in reduced negative patient outcomes. Yet, there are few studies...
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Benefit of Four-Dimensional Computed Tomography Derived Ejection Fraction of the Left Atrial Appendage to Predict Thromboembolic Risk in the Patients with Valvular Heart Disease

Kim IC, Chang HJ, Cho IJ, Shim CY, Hong GR, Heo JH, Nam HS, Kim YJ, Choi BW, Chung N

BACKGROUND AND OBJECTIVES: Decreased left atrial appendage (LAA) emptying velocity in transesophageal echocardiography (TEE) is related with higher incidence of thrombus and increased risk of stroke. Patients with valve disease...
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The Role of Microenvironment in Preserving the Potency of Adult Porcine Pulmonary Valve Stem Cells In Vitro

Chalajour , Siyahian A, Hanley FL

BACKGROUND AND OBJECTIVE: The potency of tissue resident stem cells is regulated primarily by inputs from the local microenvironment. Isolation of stem cells through enzymatic digestion of tissue may affect...
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Critical Illness Neuromyopathy Complicating Cardiac Surgery

Baek WK, Kim YS, Kim JT, Yoon BN

Critical illness neuromyopathy (CINM) is a sporadically reported disease in the setting of an intensive care unit developing in the process of managing a critical illness. The disease primarily affects...
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Outcomes of Reoperative Valve Replacement in Patients with Prosthetic Valve Endocarditis: A 20-Year Experience

Kim YW, Jung SH, Choo SJ, Chung CH, Lee JW, Kim JB

BACKGROUND: Prosthetic valve endocarditis (PVE) is a serious complication of cardiac valve replacement, and many patients with PVE require reoperation. The aim of this study was to review our institutional...
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Isoflurane's Effect on Intraoperative Systolic Left Ventricular Performance in Cardiac Valve Surgery Patients

Kim JD, Son I, Kwon WK, Sung TY, Sidik H, Kim K, Kang H, Bang J, Yeo GE, Lee DK, Kim TY

BACKGROUND: Isoflurane, a common anesthetic for cardiac surgery, reduced myocardial contractility in many experimental studies, few studies have determined isoflurane's direct impact on the left ventricular (LV) contractile function during...
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Novel Approach Toward the Generation of Tissue Engineered Heart Valve by Using Combination of Antioxidant and Detergent: A Potential Therapy in Cardiovascular Tissue Engineering

Tardalkar , Desai S, Adnaik A, Bohara R, Joshi M

To develop decellularized heart valve scaffold from porcine for heart valve regeneration. Porcine heart valves were decellularized with unique optimized approach by using 1% sodium dodecyl sulfate solution and 5%...
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Utility of a Direct 16S rDNA PCR and Sequencing for Etiological Diagnosis of Infective Endocarditis

Kim MS, Chang J, Kim MN, Choi SH, Jung SH, Lee JW, Sung H

BACKGROUND: Cases of infective endocarditis (IE) require prompt etiological diagnosis for effective treatment. Molecular methods can aid in rapid and reliable diagnosis of culture-negative IE cases. We evaluated the utility...
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Stroke Prevention in Atrial Fibrillation

Cha MJ

It is important to evaluate the risks of stroke and bleeding when screening patients with atrial fibrillation (AF), in whom anticoagulation therapy is indicated. Oral anticoagulation therapy is recommended in...
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Effect of Rosuvastatin on Bovine Pericardial Aortic Tissue Valve Calcification in a Rat Subdermal Implantation Model

Lee SH, Kim DH, Youn YN, Lee S, Joo HC, Chang BC, Yoo KJ

BACKGROUND AND OBJECTIVES: There are pathophysiologic similarities between calcification and atherosclerosis because both are the product of an active inflammatory process. The aim of this study was to examine the...
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The True Deep Femoral Artery Aneurysm: A Case Report

Jang LC, Park SS

A 55-year-old man with a palpable pulsatile mass and pain in his left thigh was presented to us. He had no history of trauma in his left leg, interventions, operation,...
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Overview of cardiac rehabilitation

Kim C

Cardiac rehabilitation (CR) is an integral component of the continuum of care for patients with cardiovascular disease. Today, the efficacy and safety of CR are well established, but the rate...
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Bioreactor Conditioning of Valve Scaffolds Seeded Internally with Adult Stem Cells

Kennamer A, Sierad L, Pascal R, Rierson N, Albers C, Harpa M, Cotoi O, Harceaga L, Olah P, Terezia P, Simionescu A, Simionescu D

The goal of this study was to test the hypothesis that stem cells, as a response to valve-specific extracellular matrix “niches” and mechanical stimuli, would differentiate into valvular interstitial cells...
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Blood Conservation Strategy during Cardiac Valve Surgery in Jehovah's Witnesses: a Comparative Study with Non-Jehovah's Witnesses

Kim TS, Lee JH, Na CY

BACKGROUND: We compared the clinical outcomes of cardiac valve surgery in adult Jehovah's Witness patients refusing blood transfusion to those in non-Jehovah's Witness patients without any transfusion limitations. METHODS: From 2005...
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Peri-procedural Management of Anticoagulation Therapy (cataract eye surgery, dental procedure and gastrointestinal endoscopy)

Chung JW

Anticoagulation therapy is widely used to prevent thromboembolism in patients with atrial fibrillation, venous thromboembolism, and mechanical heart valves. The temporary interruption of anticoagulants is common to reduce the bleeding...
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A Case of Microangiopathic Hemolytic Anemia after Myxoma Excision and Mitral Valve Repair Presenting as Hemolytic Uremic Syndrome

Park YJ, Kim SP, Shin HJ, Choi JH

Microangiopathic hemolytic anemia occurs in a diverse group of disorders, including thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and prosthetic cardiac valves. Hemolytic anemia also occurs as a rare complication after...
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New Drugs for Obesity Treatment

Kim WJ, Lee CB

There have recently been many advances in obesity treatment, including lifestyle modifications and pharmacological and surgical treatments. Specifically, pharmacological strategies have improved significantly. However, the history of the development of...
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Involvement of Immune Cell Network in Aortic Valve Stenosis: Communication between Valvular Interstitial Cells and Immune Cells

Lee SH, Choi JH

Aortic valve stenosis is a heart disease prevalent in the elderly characterized by valvular calcification, fibrosis, and inflammation, but its exact pathogenesis remains unclear. Previously, aortic valve stenosis was thought...
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