J Rhinol.  1998 May;5(1):68-71.

Surgical Repair of Cerebrospinal Fluid Rhinorrhea with Mucoperichondrial Free Graft

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Sung Kyun Kwan University, College of Medicine, Samsung Medical Center, Seoul, Korea.


Three cases of cerebrospinal fluid (CSF) rhinorrhea and anterior skull base defects were successfully treated by applying mucoperichondrial free graft through the endonasal endoscopic technique. The causes of the skull base defects were trauma in two cases and endoscopic sinus surgery in one case. The defects were located in the sphenoid sinus in one case and the fovea ethmoidalis in two cases. In these cases, contralateral side septal mucoperichondrial free grafts were used to seal the defects and were supported with fibrin glue and Spongostan(R). Endoscopic repair with mucoperichondrial free graft appeared to be a safe and successful approach to the treatment of the anterior skull base defects.


Cerebrospinal fluid rhinorrhea; Endoscopic repair; Mucoperichondrial free graft
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