J Korean Ophthalmol Soc.  2004 May;45(5):732-735.

Clinical Consideration of Prednisolone Induced Cataract

• Kim KS
• Joo CK

Abstract

PURPOSE
The purpose of this paper was to examine the correlation between the development of posterior subcapsular cataract and the dosage and duration of systemic steroid therapy. METHODS: Twenty-two eyes which underwent cataract surgery at our ophthalmologic department were enrolled, along with 20 randomly selected eyes, which received prednisolone therapy at least for 1 year. We examined prednisolone dosage, duration and systemic disorders. We compare daily prednisolone dosage, and duration between the subcapsular opacity group and the non-subcapsular opacity group. SPSS, with 2 way- ANOVA system, was used for statistical analysis. RESULTS: The development of posterior subcapsular cataract was correlated with the daily prednisolone dosage, but not with the duration of prednisolone therapy (p<0.05). CONCLUSIONS: Careful attention to the daily steroid dosage is required to prevent posterior subcapsular cataract formation.

Keyword

Cataract; Prednisolone; Systemic steroid

MeSH Terms

Cataract*
Prednisolone*
Prednisolone