J Korean Radiol Soc.  2002 Mar;46(3):251-255. 10.3348/jkrs.2002.46.3.251.

MR Findings of Ossifying Fibroma with Pathologic Correlation

Affiliations
  • 1Department of Diagnostic Radiology, Korea Cancer Center Hospital. hoon@kcch.re.kr

Abstract

PURPOSE
To compare the MR imaging findings of ossifying fibroma with the histopathologic findings.
MATERIALS AND METHODS
In eight patients (M:F=1:7; age range, 1-25 years) with pathologically proven ossifying fibroma, plain film and MR images were retrospectively analyzed in terms of signal intensity, homogeneity and patterns of contrast enhancement. The MR imaging findings and histopathology were correlated. Using 1.0-T and 1.5-T MR machines, axial T1 and T2 images and gadolinium-enhanced axial and sagittal T1 images were obtained.
RESULTS
In all cases, iso-signal intensity to muscle was observed on T1-weighted images, and high signal intensity on T2-weighted images. After intravenous injection of gadolinium-DTPA in seven cases, intense contrast enhancement was seen in all lesions, which were homogenous on T1, T2, and enhanced MR images. Moderate cellularity of fibrous tissue, with even distribution of osteoid and an absence of secondary changes such as hemorrhage or cystic change were revealed by pathologic examination.
CONCLUSION
Ossifying fibroma shows strong enhancement and homogenous signal intensity on MR images.The homogeneity of the MR signal depends on the even distribution of osteoid and an absence of secondary changes such as hemorrhage or cystic change.

Keyword

Bone neoplasms; Bone neoplasms, MR

MeSH Terms

Bone Neoplasms
Fibroma, Ossifying*
Hemorrhage
Humans
Injections, Intravenous
Magnetic Resonance Imaging
Retrospective Studies
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