Korean J Med.  2004 Aug;67(2):208-212.

A case of intestinal perforation in Churg-Strauss syndrome patient

Affiliations
  • 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dcchoi@smc.samsung.co.kr
  • 2Department of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Churg-Strauss syndrome (CSS) is a disorder characterized by systemic small-to-medium vessel vasculitis, extravascular granulomas and hypereosinophilia. Gastrointestinal manifestations can occur in 37~62% of CSS patients but intestinal perforation is very rarely demonstrated. We report a case of 34-year-old man with CSS, who presented with intestinal perforation three months after diagnosed as CSS. Emergency laparotomy was performed and jejunal ulcers with perforation were found. Partial jejunectomy was performed. Pathologic findings of the resected specimen were interpretated as mucosal ulcerations which are considered to be caused by ischemia secondary to the vasculitis and eosinophilic infiltration. Since the operation, the patient has been asymptomatic.

Keyword

Churg-Strauss syndrome; Intestinal perforation

MeSH Terms

Adult
Churg-Strauss Syndrome*
Emergencies
Eosinophils
Granuloma
Humans
Intestinal Perforation*
Ischemia
Laparotomy
Ulcer
Vasculitis
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