J Korean Radiol Soc.  1997 Sep;37(3):379-384.

Contrast-Enhanced Turbo Spin-Echo(TSE) T1-weighted Imaging: Improved Contrast of Enhancing Lesions

Affiliations
  • 1Department of Diagnostic Radiology, College of Medicine, Inje University.

Abstract

PURPOSE
The purpose of this study was to evaluate the effect of contrast improvement of enhancing brain lesions by inherent magnetization transfer effect in turbo spin-echo (TSE) T1-weighted MR imaging.
MATERIALS AND METHODS
Twenty-six enhancing lesions of 19 patients were included in this study. Using a 1.0T superconductive MR unit, contrast-enhanced SE T1-weighted images (TR=600 msec, TE=12 msec, NEX=2, acquisition time=4 min 27sec) and contrast-enhanced TSE T1-weighted images (TR=600 msec, TE=12 msec, NEX=2, acquisition time=1min 44sec) were obtained. Signal intensities at enhancing lesions and adjacent white matter were measured in the same regions of both images. Signal-to-noise ratio (SNR) of enhancing lesions and adjacent white matter, and contrast-to-noise ratio (CNR) and lesion-to-background contrast (LBC) of enhancing lesions were calculated and statistically analysed using the paired t-test.
RESULTS
On contrast-enhanced TSE T1-weighted images, SNR of enhancing lesions and adjacent white matter decreased by 18%(p<0.01) and 32% (p<0.01), respectively, compared to contrast-enhanced SET1-weighted images. CNR and LBC of enhancing lesions increased by 16% (p<0.05) and 66% (p<0.01), respectively.
CONCLUSION
Due to the proposed inherent magnetization transfer effects in TSE imaging, contrast-enhanced T1-weighted TSE images demonstrated a statistically significant improvement in CNR and LBC, compared to conventional contrast-enhanced T1-weighted SE images, and scan time was much shorter.

Keyword

Magnetic resonance(MR), technology; Magnetic resonance(MR), rapid imaging; Magnetic resonance(MR),magnetization transfer contrast

MeSH Terms

Brain
Humans
Magnetic Resonance Imaging
Signal-To-Noise Ratio
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