J Korean Radiol Soc.  1994 Sep;31(3):529-534.

MR Imaging of Gestational Trophoblastic Tumors

• Kim HH
• Lee JH
• Song HH
• Lee EJ
• Kim TG
• Park JB
• Ha HK
• Ro SC
• Jee MK
• Chung JG

Abstract

PURPOSE
To evaluate the MR findings of gestational trophoblastic tumor(GTT) in correlation with pathological results.
MATERIALS AND METHODS
Nine patients who confirmed the diagnosis (four choriocarcinomas and five invasive moles) constituted the basis of our study. Pathologic specimens were taken from the tumors corresponding to the regions of interest on MR images. The MR images were analyzed in respect of the morphology and signal intensity of the tumors, uterine and adnexal vascularity, and the adnexal lesion.
RESULTS
The MR findings of four choriocarcinomas were well-defined, hemorrhagic masses with central necrosis;the masses were hyperintense on Tl-weighted images. In contrast, the five invasive moles showed irregular and permeative masses with densely enhanced solid components and tiny cystic lesions. The trophoblastic proliferation, coagulation necrosis, and molar villi had variable signal intensities on Tl-and T2-weighted images.
CONCLUSION
Our results suggest that MR imaging is a promising tool for noninvasive morphologic analysis of GTTS.

MeSH Terms

Choriocarcinoma
Diagnosis
Female
Humans
Hydatidiform Mole, Invasive
Magnetic Resonance Imaging*
Molar
Necrosis
Pregnancy
Trophoblastic Neoplasms*
Trophoblasts*