J Korean Rheum Assoc.  2003 Dec;10(4):456-461.

A Case of Cytomegalovirus Pneumonia and Retinitis in a Patients with Systemic Lupus Erythematosus

• Han SH
• Sohn YJ
• Park MA
• Lee S
• Ryu SH
• Lim TH
• Jung DS
• Son YK
• Roh MS
• Park MK
• Lee SW
• Chung WT

Abstract

Cytomegalovirus (CMV) is the member of the herpesviridae of virus, which are large DNA viruses that share the biologic properties of latency and reactivation. In patients with advanced acquired immune deficiency syndrome (AIDS) and those immunocompomised due to bone marrow transplantation or solid organ transplantation, CMV infection is the major cause of morbidity and mortality. CMV pneumonia is the most severe complication of these CMV disease. There have been reported a few cases of CMV interstitial pneumonitis occurring in a patient with SLE after intensive immunosuppressive therapy with prednisolone and cyclophosphamide, and there has been reported a case in Korea. Then we report a case of CMV pneumonia and retinitis occurring in a patient with SLE who was being treated with high dose steroid for 1 month, and was treated with ganciclovir and immunoglobulin.

Keyword

SLE; CMV infection; Pneumonia; CMV retinitis

MeSH Terms

Acquired Immunodeficiency Syndrome
Bone Marrow Transplantation
Cyclophosphamide
Cytomegalovirus*
DNA Viruses
Ganciclovir
Herpesviridae
Humans
Immunoglobulins
Korea
Lung Diseases, Interstitial
Lupus Erythematosus, Systemic*
Mortality
Organ Transplantation
Pneumonia*
Prednisolone
Retinitis*
Transplants
Cyclophosphamide
Ganciclovir
Immunoglobulins
Prednisolone