Korean J Dermatol.  2012 Oct;50(10):880-883.

Ulcerative Infantile Hemangioma Treated with Topical Timolol

Affiliations
  • 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. Kyuhkim@snu.ac.kr

Abstract

Therapeutic options for infantile hemangioma are limited. The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. However, systemic propranolol carries a risk of serious side effects, including bradycardia, hypoglycemia, arrhythmias, hypotension and bronchospasm. Recently, treatment of infantile hemangioma with topical timolol (nonselective beta-blocker similar to propranolol) has been reported. We treated successfully the perineal ulcerative hemangioma with topical timolol. We believe that timolol is a safe and effective topical agent and should be strongly considered as one of good therapeutic options for hemagnioma.

Keyword

Beta blocker; Hemangioma; Timolol; Topical treatment

MeSH Terms

Arrhythmias, Cardiac
Bradycardia
Bronchial Spasm
Hemangioma
Hypoglycemia
Hypotension
Propranolol
Timolol
Ulcer
Propranolol
Timolol
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