Korean J Gastroenterol.  1999 Jun;33(6):776-785.

Efficacy of PyloriTek Test for Helicobacter pylori Detection

• Lim CN
• Kim N
• Choi WR
• Won KH
• Lee SH
• Lim SH
• Lee KH
• Koo MS
• Choi SE

Abstract

BACKGROUND/AIMS: CLO test is widely used as a rapid urease test. However, it needs 24 hours to diagnose negativity of Helicobacter pylori infection. Recently, PyloriTek test which is a new reagen strip rapid urease test is introduced. This new method needs only 60 minutes for diagnosing H. pylor infection. To evaluate the efficacy of the new test, we compared the sensitivity and specificity of PyloriTek test with those of CLO test, Gram stain, Giemsa stain and culture.
METHODS
Five differen test methods (PyloriTek test, CLO test, Gram stain, Giemsa stain and culture) were taken in 100 patients with gastric ulcer or duodenal ulcer to diagnose H. pylori infection.
RESULTS
The sensitivity and the specificity of each test were as follows: 95.6% and 87.8% in PyloriTek test; 91.8% and 95.1% in CLO test; 94.3% and 97.6% in Gram stain; 81.3% and 100% in Giemsa stain; 50.0% and 100% in culture. Among these five tests, the sensitivities of PyloriTek test, CLO test and Gram stain were similarly higher than those of Giemsa stain and culture. The specificity of PyloriTek tes (87.8%) was relatively lower than those of the other four tests.
CONCLUSIONS
Although the specificity of PyloriTek test was relatively low, this test appears to be useful because of short testing time and high sensitivity.

Keyword

Helicobacter pylori; PyloriTek test

MeSH Terms

Azure Stains
Duodenal Ulcer
Helicobacter pylori*
Helicobacter*
Humans
Sensitivity and Specificity
Stomach Ulcer
Urease
Azure Stains
Urease