Korean J Gastrointest Endosc.
2007 Aug;35(2):100-104.
A Case of Giant Brunner's Gland Adenoma Originating from the Gastric Pylorus Associated with Severe Anemia and Intussusception
- Affiliations
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- 1Department of Internal Medicine, Suyeong-Hanseo Hospital, Korea.
- 2Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. jsjang@dau.ac.kr
- 3Department of Diagnostic Radiology, Dong-A University College of Medicine, Busan, Korea.
- 4Department of Pathology, Dong-A University College of Medicine, Busan, Korea.
Abstract
- Brunner's gland adenoma is characterized by benign proliferation of the normal Brunner's gland, and is a relatively rare disease that accounts for only 10% of benign duodenal tumors. It is usually found in the bulb and second portion of the duodenum, but is rarely found in the pylorus. The clinical manifestations vary from non-specific upper abdominal symptoms to obstruction, intussusception and gastrointestinal hemorrhage. It is a benign lesion but rarely undergoes malignant transformation. Management of Brunner's gland adenoma involves complete removal of the lesion. We experienced a 43-year-old man who had complained of melena and dyspnea on exertion. An esophagogastroduodenoscopy and computed tomography of the upper gastrointestinal tract demonstrated the presence of a 5.5x4.0 cm sized hyperemic and lobulated large mass with hemorrhage that originated from the pylorus and was intussuscepted into the duodenum. Resection of the tumor revealed that it was a Brunner's gland adenoma on a histological examination.
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