Korean J Hepatol.  2000 Dec;6(4):524-529.

A Case of Focal Nodular Hyperplasia of the Liver

Affiliations
  • 1Department of Internal Medicine, Liver Research Institute Kyungpook National University College of Medicine, Taegu, Korea.
  • 2Department of Pathology, Liver Research Institute Kyungpook National University College of Medicine, Taegu, Korea.
  • 3Department of Radiology, Liver Research Institute Kyungpook National University College of Medicine, Taegu, Korea. whckd@hitel.net

Abstract

Focal nodular hyperplasia (FNH) is a rare benign hepatic tumor occurring predominantly in women of childbearing age. Generally oral contraceptive is not associated with FNH but might accentuate the vascular abnormalities which may cause the lesion to enlarge and, very rarely, to rupture. FNH is typically asymptomatic and seldom bleeds. Often it is incidentally observed during imaging procedures performed for some other reasons. The histologic feature of FNH is characterized by areas of localized growth of mature hepatocytes and septal fibrosis. Surgical resection is seldom required because of the benign nature of the lesion and its lack of significant complication. We experienced a case of focal nodular hyperplasia without liver cirrhosis confirmed by surgical resection and histologic examination. in a 47-year-old man.

Keyword

Focal nodular hyperplasia(FNH); septal fibrosis

MeSH Terms

Female
Fibrosis
Focal Nodular Hyperplasia*
Hepatocytes
Humans
Liver Cirrhosis
Liver*
Middle Aged
Rupture
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