Korean J Nephrol.
2010 Nov;29(6):772-775.
Proliferative Glomerulopathy with Unusual Subendothelial Deposits of Striated Structure in Multiple Myeloma
- Affiliations
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- 1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. kim_dajung@hanmail.net
- 2Department of Pathology, Seoul National University Hospital, Seoul, Korea.
Abstract
- A 50-year-old woman was admitted for the evaluation of proteinuria and renal biopsy. On the basis of the serum monoclonal protein, marrow plasma cell dyscrasia and end organ damage (nephrotic range proteinuria), multiple myeloma was diagnosed. A renal biopsy showed a membranoproliferative glomerulonephritis pattern of injury and unusual organized deposits of striated structure in the subendothelial space, which were identified as non-amyloid non-immunoglobulin-derived deposits. These deposits contained regularly stacked straight electron-dense bands, which have not been described in the setting of paraproteinemia and/or plasma cell dyscrasia.
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