Korean J Nephrol.
2005 Mar;24(2):320-325.
A Case of Minimal Change Disease during Chemotherapy of Bronchogenic Adenocarcinoma
- Affiliations
-
- 1Department of Internal Medicine, Soonchunhyang University Medical College, Bucheon, Korea. sd7hwang@schbc.ac.kr
- 2Department of Pathology, Soonchunhyang University Medical College, Bucheon, Korea.
Abstract
- A 60 year-old woman was admitted with generalized edema. The patient had bronchogenic adenocarcinoma which was diagnosed 8 months ago, and treated with 3 cycles of etoposide and cisplatin and 6 cycles of paclitaxel and carboplatin. After completion of chemotherapeutic cycles, massive proteinuria (18, 018 mg/day) developed. Renal biopsy revealed minimal change disease, acute tubular necrosis and chronic interstitial nephritis. In spite of continuous chemotherapy, there was no evidence of remission of cancer lesion on a serial consecutive radiographic study. She quitted continuing chemotherapy, and alternative day high dose of prednisolone was initiated for minimal change disease. Proteinuria was decreased dramatically (180 mg/day) after 2 months, and did not recur during tapering of prednisolone. Although bone metastasis on the right femur was newly detected after 2 months, proteinuria did not develop. We experienced minimal change disease during chemotheraphy of bronchogenic adenocarcinoma, thus we report it with article review.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A Case of Primary Small Cell Bronchogenic Carcinoma Detected by Bronchoscopy in a Child
- A Case of Adenocarcinoma Arising within Intra-Abdominal Bronchogenic Cyst
- Solitary Metastasis of Bronchogenic Adenocarcinoma to the Internal Auditory Canal: A Case Report
- Minimal Change Disease Associated with Gastric Adenocarcinoma and Multiple Liver Metastasis
- A case of minimal deviation adenocarcinoma originated from uterine endocervix
