Korean J Spine.  2011 Sep;8(3):240-243. 10.14245/kjs.2011.8.3.240.

Monostotic Paget's Disease of the Lumbar Spine Mimicking Vertebral Metastasis: A Case Report

Affiliations
  • 1Department of Neurosurgery, Research Institute of Clinical Medicine, Institute for Medical Science, Chonbuk National University Medical School and Hospital, Jeonju, Korea. spineeun@chonbuk.ac.kr

Abstract

Paget's disease of the bone is the second-most-common metabolic bone disease. However, it is rarely found in the Far East. Vertebral Paget's disease usually occurs at multiple vertebral levels, with less than 20% of vertebral Paget's disease being monostotic. Here, we present a rare case of monostotic vertebral Paget's disease, which we initially misdiagnosed as a spinal metastasis. A 34-year-old man was admitted with a one-month history of lower back pain. Initially, computed tomography of the lumbar spine showed an osteolytic change of the L4 and mild expansion of the L4 vertebral body. Subsequently, magnetic resonance imaging showed a highly homogenously enhanced L4 vertebral body. We performed positron-emission tomography, bone scan, and tumor marker evaluation. However, we could not detect any likely primary origin of the spinal metastasis. Therefore, we carried out a needle bone biopsy under fluoroscopic guidance, and the bone specimen revealed Paget's disease of the bone.

Keyword

Paget's disease; Lumbar vertebra; Bone scintigraphy

MeSH Terms

Adult
Biopsy
Bone Diseases, Metabolic
Far East
Humans
Low Back Pain
Magnetic Resonance Imaging
Needles
Neoplasm Metastasis
Positron-Emission Tomography
Spine
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