J Korean Neurosurg Soc.
1999 Aug;28(8):1226-1231.
Prevention and Medical Management of Vasospasm
- Affiliations
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- 1Department of Neurosurgery, School of Medicine, Wonkwang University, Iksan, Korea.
Abstract
- Numerous approaches to the prevention and treatment of cerebral vasospasm have been made. Its etiology and pathogenesis are still not well understood, and there is no animal model that duplicates all of the key aspects of human cerebral vasospasm. It is therefore not surprising that most of the attempts to prevent or treat this condition have failed. Since 1980, there has been some progress toward the satisfactory management of this detrimental condition, but much remains to be done. In the present article, experimental therapies are examined in detail, followed by a review of promising new treatments presently in clinical trials and generally accepted management in reducing the ischemic complications related to cerebral vasospasm.
