J Korean Neurosurg Soc.
1999 Aug;28(8):1194-1198.
Epithelioid Hemangioendothelioma
- Affiliations
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- 1Department of Neurosurgery, Inha Hospital, College of Medicine, Inha University, Kyunggido, Korea.
Abstract
- Epithelioid hemangioendothelioma is a rare vascular neoplasm characterized by epithelioid tumor cells and borderline biologic behavior. We present a case of grade III malignant epithelioid hemangioendothelioma of the skull and brain parenchyme in a 58-year-old female. The tumor consisted of loose aggregates of epithelioid cells with a focal small nest pattern and tumor cells displayed frequent intracytoplasmic vacuoles and contained areas with significant atypia and mitotic activity(more than 2/10 HPF). Immunohistochemically, the tumor cells showed positive staining for facor VIII-RGA and vimentin. Radiological and histopathologic characteristics of this tumor with a review of pertinent literature is presented.
