J Korean Neurosurg Soc.
2005 Jul;38(1):54-60.
Three Cases of Intracranial Clear Cell Meningioma
- Affiliations
-
- 1Department of Neurosurgery, Chonnam National University Hospital & Medical School, Gwangju, Korea. sjung@chonnam.ac.kr
- 2Department of Pathology, Chonnam National University Hospital & Medical School, Gwangju, Korea.
Abstract
- The clear cell meningioma(CCM) is a rare and recently described as a histologic variant of meningioma. It has been identified and included in new World Health Organization(WHO) classification of the Central Nervous System(CNS) tumors recently. The CCMs are histologically characterized by sheets of spindled to polygonal cells with clear cytoplasm, which is the expression of high glycogen concentration. The CCMs occur in younger patients and usually are located in the spinal canal and posterior fossa. The most interesting aspect of CCM is the high recurrence rate and aggressiveness. Poor outcome has been shown in intracranial and spinal tumor location, but the indicators that predict outcome have not been established. Until now 22 intracranial CCM cases had been reported in English literature and 3 cases in Korean. The authors report two cases of CCM located at cerebral convexity and one at cavernous sinus those were totally removed (Simpson Grade I~II) by subfrontal, frontal and orbitocranial approaches. The clinical, radiological, histopathological, and neurosurgical features of these cases are discussed with the relevant literatures.
