J Korean Neurol Assoc.  1999 Sep;17(5):780-782.

A Case of Leptomeningeal Metastasis Presented with Bilateral Loss of Vision

• Kim SH
• Koh SB
• Lee KW

Abstract

We describe an unusual case of leptomenigeal carcinomatosis presented with bilateral blindness. A 67-year old male had been suffering from progressive blindness for the past 2 months. Initially, the symptom developed in the right eye but quickly spread to the left eye becoming bilateral with complete vision loss in a matter of weeks. He did not show any other focal neurological signs and did not have a history of malignancy. An examination of the cerebrospinal fluid revealed metastatic adenocarcinoma. As this case indicated, the patients of leptomeningal metastasis may present with acute or subacute blindness, even in the absence of other focal neurological deficits.

Keyword

Blindness; Leptomeningeal metastasis; Presenting symptom

MeSH Terms

Adenocarcinoma
Aged
Blindness
Carcinoma
Cerebrospinal Fluid
Humans
Male
Neoplasm Metastasis*