J Korean Fract Soc.  2006 Jan;19(1):67-71. 10.12671/jkfs.2006.19.1.67.

Negative Pressure Wound Therapy for Traumatic Soft Tissue Defects

• Lee KB
• Choi J
• Moon ES
• Yoon TR
• Lim KY

• KMID: 2063826
• DOI: http://doi.org/10.12671/jkfs.2006.19.1.67

Abstract

PURPOSE: To evaluate the negative pressure wound therapy for traumatic soft tissue defects by vacuum-assised closure (V.A.C.(R)).
MATERIALS AND METHODS
33 patients with traumatic soft tissue defects were treated by using V.A.C.(R) which removes edema fluid, eliminates an extrinsic cause of microcirculatory embarrassment and may directly stimulate cellular proliferation of reparative granulation tissue. We removed all necrotic tissue prior to application of the V.A.C.(R). The foam dressing was placed into direct contact with wound and was changed every 48~72 hours. The setting for vacuum pump was continuous pressure of 100 to 125 mm Hg. C-reactive protein was checked to evaluate wound infection. We measured wound size and total duration of treatment.
RESULTS
Mean duration of treatment was 25.2 days and mean decrease of wound size was 31.9%. The concentration of CRP after V.A.C.(R) therapy reduced by day 8 below 1.0 mg/dl and gradually decreased to normal level by day 10. All patients showed hastened wound healing by rapid formation of granulation tissue.
CONCLUSION
Negative pressure wound therapy is useful in patients with traumatic soft tissue defects, which reduces treatment duration and cost by rapid wound healing and effective infection control.

Keyword

Soft tissue defect; Negative pressure wound therapy

MeSH Terms

Bandages
C-Reactive Protein
Cell Proliferation
Edema
Granulation Tissue
Humans
Infection Control
Negative-Pressure Wound Therapy*
Vacuum
Wound Healing
Wound Infection
Wounds and Injuries
C-Reactive Protein