Korean J Otorhinolaryngol-Head Neck Surg.  2015 Sep;58(9):641-645. 10.3342/kjorl-hns.2015.58.9.641.

Radiologically Unusual Presentation of Cholesterol Granuloma in the Sphenoid Sinus

Affiliations
  • 1Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea. hyungjucho@yuhs.ac
  • 2Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
  • 3The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Cholesterol granuloma is a histopathological diagnosis with features of cholesterol clefts, foreign body giant cells, and macrophages filled with hemosiderin. It is commonly found in the mastoid or petrous apex, but the involvement of paranasal sinuses is very rare. Radiologically, cholesterol granuloma show typical findings of hyperintense signals on both T1- and T2-weighted images on magnetic resonance imaging (MRI). We report two cases of cholesterol granuloma in the sphenoid sinus, which were first misinterpreted as mucoceles due to unusual MRI images.

Keyword

Cholesterol granuloma; Magnetic resonance imaging; Mucocele; Sphenoid sinus

MeSH Terms

Cholesterol*
Diagnosis
Giant Cells, Foreign-Body
Granuloma*
Hemosiderin
Macrophages
Magnetic Resonance Imaging
Mastoid
Mucocele
Paranasal Sinuses
Sphenoid Sinus*
Cholesterol
Hemosiderin
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