Korean J Thorac Cardiovasc Surg.
2002 Jan;35(1):36-42.
Results of Surgical Management in Patients with Cardiac and Arterial Manifestations of Behcet's Syndrome
- Affiliations
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- 1Department of Diagnostic Radiology, Yonsei University College of Medicine, Korea. dyl@yumc.yonsei.ac.kr
- 2Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Korea.
Abstract
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BACKGROUND: To evaluate the efficiency of surgical treatment in patients with cardiac valvular and arterial involvement of Behcet's syndrome.
MATERIAL AND METHOD: 12 patients underwent surgical treatment due to the valvular heart diseases and the various arterial diseases associated with Behcet's syndrome over 7 years; 6 with valvular heart disease, 1 with annuloaortic ectasia, 1 with ascending aortic aneurysm, 4 with pseudoaneurysms in abdominal aorta(n=2), carotid artery(n=1), and popliteal artery(n=1). All 12 patients had received valvular replacement(n=6) and the artificial(n=5) or autologous(n=1) graft interposition. We followed the results of these surgical treatments.
RESULT: Operations were technically successful in all 12 patients and peri-operative complication was not demonstrated. However, 10 patients had recurrences; 6 with valvular dehiscence, 3 with pseudoaneurysm at anastostomosis site, and 1 with aorto-duodenal fistula. The duration of recurrence was 1 to 55 months(mean: 15.7+/-16.2 months). 7 patients underwent the second operation and among them, 4 patients showed repeated recurrences. Overall, 5 patients died 2 to 25 months after the operation(mean: 13.6 months), because of the bleeding at the anastomosis site. Five patients did not present recurrence after the first(n=2) or the second operation(n=3) and their follow up duration was 5 to 60 months(mean: 45.8+/-41.7 months). Five patients received immuno-suppressive therapy after the first(n=2) and second operation(n=3). Three did not shown recurrence for the 13, 29 and 33 months.
CONCLUSION
Post-operative prognosis of arterial manifestation of Behcet's syndrome was not encouraging and if possible, other treatment strategy should be considered.