Korean J Urol.  1994 Oct;35(10):1108-1112.

The Occurrence of Antisperm Antibodies in Patients of Scrotal Diseases

• Kim KB
• Park BJ
• Suh HS

Abstract

The aim of this investigation was to determine the incidence of sperm antibodies in serum using indirect immunobead test (IBT) in 113 patients of scrotal disease. The results of this survey showed that 17.7% of 113 men had antisperm antibodies of IgG and/or IgA class bound to the surface of at least 20% of motile spermatozoa of normal donor. There were positive immunobead test in 16 of 36(44.4% ) vasovasostomy patients, 1 of 18 testicular trauma, 1 of 15 primary infertility, 1 of 4 obstructive infertility, 1 of 7 hydrocele. There were no statistical differences in sperm count, sperm morphology between the groups of patients with positive or negative IBT results. As for the immunoglobulins, the most frequent class was IgG, and in terms of morphological sites, tail binding was most frequent. The results of this investigation therefore suggest that the IBT is an excellent test for sperm antibodies in scrotal disease.

Keyword

Immunobead; Antisperm antibody; Scrotal disease

MeSH Terms

Antibodies*
Humans
Immunoglobulin A
Immunoglobulin G
Immunoglobulins
Incidence
Infertility
Male
Sperm Count
Spermatozoa
Tissue Donors
Vasovasostomy
Antibodies
Immunoglobulin A
Immunoglobulin G
Immunoglobulins