Chonnam Med J.  1998 Dec;34(2):177-181.

Detection of Coronary Stent Restenosis using a Fast Protocol of Tc-99m Tetrofosmin Single Photon Emission Computed Tomography

• Bom HS
• Jeong MH
• Song HC
• Min JJ
• Jeong HJ
• Kim JW
• Ahn YK
• Kang JC

Abstract

The purpose of this study was to evaluate the feasibility of a fast one-day rest-stress imaging protocol using Tc-99m tetrofosmin (TF) single photon emission computed tomography (SPECT) in a pig coronary stent restenosis model. Seven juvenile pigs were underwent coronary artery angioplasty with oversized balloon catheters, followed by hepaMed stent insertion. One pig, a control, was underwent sham operation. One month later, Tc-99m TF SPECT was done using a dual-head rotating gamma camera. A fast imaging protocol which took only 50 minutes to complete was used. No pigs died during the study. Control pig showed no perfusion defects in the myocardium. Among seven pigs of experimental group, two showed reversible perfusion defects. Angiographic stenosis of the two were 33.8 and 15.3 per cents, and pathologic stenosis of them were 56.1 and 33.7 per cents, respectively. Therefore, the fast imaging protocol was feasible in a pig model of coronary stent restenosis.

Keyword

Coronary stent restenosis; Tc-99m tetrofosmin; fast imaging protocol; SPECT

MeSH Terms

Angioplasty
Catheters
Constriction, Pathologic
Coronary Vessels
Gamma Cameras
Myocardium
Perfusion
Stents*
Swine
Tomography, Emission-Computed, Single-Photon*