Infect Chemother.  2012 Aug;44(4):299-302. 10.3947/ic.2012.44.4.299.

Cat-Scratch Disease: A Case Report and Literature Review of Human and Animal Studies Performed in Korea

• Kim MH
• Kim BN
• Han TH

• KMID: 2045550
• DOI: http://doi.org/10.3947/ic.2012.44.4.299

Abstract

Cat-scratch disease is a self-limited zoonotic disease characterized by regional lymphadenopathy and fever. It is caused by Bartonella henselae, less frequently by B. clarridgeiae, and is transmitted to humans by scratches or bites from cats and dogs. Up to now, only a handful of cases have been reported in Korea. However, the number of pet cats and dogs is increasing in Korea and thus more frequent human contact with cats and dogs is expected. We present a case of cat-scratch disease diagnosed by indirect immunofluorescence assay and analysis of polymerase chain reaction results, and twenty a literature review of Bartonella infections in humans and animals in Korea.

Keyword

Bartonella; Bartonella henselae; Cat-scratch Disease; Lymphadenitis

MeSH Terms

Animals
Bartonella
Bartonella henselae
Bartonella Infections
Bites and Stings
Cat-Scratch Disease
Cats
Dogs
Fever
Fluorescent Antibody Technique, Indirect
Hand
Humans
Korea
Lymphadenitis
Lymphatic Diseases
Polymerase Chain Reaction

Reference

1. Kaiser PO, Riess T, O'Rourke F, Linke D, Kempf VA. Bartonella spp.: throwing light on uncommon human infections. Int J Med Microbiol. 2011. 301:7–15.

2. Anderson BE, Neuman MA. Bartonella spp. as emerging human pathogens. Clin Microbiol Rev. 1997. 10:203–219.

3. Florin TA, Zaoutis TE, Zaoutis LB. Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. Pediatrics. 2008. 121:e1413–e1425.

4. Chomel BB, Boulouis HJ, Maruyama S, Breitschwerdt EB. Bartonella spp. in pets and effect on human health. Emerg Infect Dis. 2006. 12:389–394.

5. Breitschwerdt EB, Kordick DL. Bartonella infection in animals: carriership, reservoir potential, pathogenicity, and zoonotic potential for human infection. Clin Microbiol Rev. 2000. 13:428–438.

6. Windsor JJ. Cat-scratch disease: epidemiology, aetiology and treatment. Br J Biomed Sci. 2001. 58:101–110.

7. Saisongkorh W, Rolain JM, Suputtamongkol Y, Raoult D. Emerging Bartonella in humans and animals in Asia and Australia. J Med Assoc Thai. 2009. 92:707–731.

8. Jackson LA, Spach DH, Kippen DA, Sugg NK, Regnery RL, Sayers MH, Stamm WE. Seroprevalence to Bartonella quintana among patients at a community clinic in downtown Seattle. J Infect Dis. 1996. 173:1023–1026.

9. Chung JY, Koo JW, Kim SW, Yoo YS, Han TH, Lim SJ. A case of cat scratch disease confirmed by polymerase chain reaction for Bartonella henselae DNA. Korean J Pediatr. 2005. 48:789–792.

10. Chung JY, Han TH, Kim BN, Yoo YS, Lim SJ. Detection of Bartonella henselae DNA by polymerase chain reaction in a patient with cat scratch disease: a case report. J Korean Med Sci. 2005. 20:888–891.

11. Yoon HJ, Lee WC, Choi YS, Cho S, Song YG, Choi JY, Kim CO, Kim EJ, Kim JM. Cervical lymphadenitis in a patient coinfected with Toxoplasma gondii and Bartonella henselae. Vector Borne Zoonotic Dis. 2010. 10:415–419.

12. Suh B, Chun JK, Yong D, Lee YS, Jeong SH, Yang WI, Kim DS. A report of cat scratch disease in Korea confirmed by PCR amplification of the 16S-23S rRNA intergenic region of Bartonella henselae. Korean J Lab Med. 2010. 30:34–37.

13. Chae MB, Lee JY, Kwak YG, Park SH, Lim HJ, Park SW, Chung MH, Kim MK, Kang JS. Prevalence of antibodies to Bartonella henselae and Bartonella quintana in Korean patients with lymphadenopathy. Korean J Infect Dis. 2002. 34:305–310.

14. Chung JY, Kim SW, Han TH, Lim SJ. Detection of the Bartonella henselae gene sequence in lymph nodes of children with Kikuchi's disease. Pediatrics. 2005. 115:1112.

15. Lee JY, Kang JS, Kim MK, Hwang TS, Kwak YG, Chae MB, Jang CS, Kim IK, Seo DB, Chung MH. The prevalence of Bartonella henselae infection in Korean feral cats. Korean J Infect Dis. 2001. 33:319–324.

16. Kim CM, Kim JY, Yi YH, Lee MJ, Cho MR, Shah DH, Klein TA, Kim HC, Song JW, Chong ST, O'Guinn ML, Lee JS, Lee IY, Park JH, Chae JS. Detection of Bartonella species from ticks, mites and small mammals in Korea. J Vet Sci. 2005. 6:327–334.

17. Han TH, Chung JY, Seong HK, Kim SW. Molecular detection of Bartonella henselae DNA from fleas obtained from dogs, Korea. Korean J Pediatr. 2006. 49:983–986.

18. Chae JS, Yu do H, Shringi S, Klein TA, Kim HC, Chong ST, Lee IY, Foley J. Microbial pathogens in ticks, rodents and a shrew in northern Gyeonggi-do near the DMZ, Korea. J Vet Sci. 2008. 9:285–293.

19. Kim YS, Seo KW, Lee JH, Choi EW, Lee HW, Hwang CY, Shin NS, Youn HJ, Youn HY. Prevalence of Bartonella henselae and Bartonella clarridgeiae in cats and dogs in Korea. J Vet Sci. 2009. 10:85–87.

20. Song JY, Cheong HJ. Diagnosis and treatment of cervical lymphadenitis from a standpoint of infectious disease specialists. Infect Chemother. 2008. 40:76–82.

21. Cleri DJ, Ricketti AJ, Vernaleo JR. Fever of unknown origin due to zoonoses. Infect Dis Clin North Am. 2007. 21:963–996. viii-ix

22. Rabinowitz PM, Gordon Z, Odofin L. Pet-related infections. Am Fam Physician. 2007. 76:1314–1322.

23. Koehler JE, Duncan LM. Case records of the Massachusetts General Hospital. Case 30-2005. A 56-year-old man with fever and axillary lymphadenopathy. N Engl J Med. 2005. 353:1387–1394.

24. Kravetz JD, Federman DG. Cat-associated zoonoses. Arch Intern Med. 2002. 162:1945–1952.

25. Cho CW, Seon SS. Study on booming pet industry in Jeollanamdo. Accessed 30 September 2011. Available at: http://www.jeri.re.kr/upfiles/vision/vision-68-3.pdf.