J Korean Assoc Oral Maxillofac Surg.  2012 Jun;38(3):166-170. 10.5125/jkaoms.2012.38.3.166.

Calcifying epithelial odontogenic tumor associated with the left mandibular first premolar: a case report and literature review

• Kim WK
• Kim MS
• Lee EM
• Cha JW
• Choi BY
• Kim BC
• Min SK
• Lee J

• KMID: 2043846
• DOI: http://doi.org/10.5125/jkaoms.2012.38.3.166

Abstract

Calcifying epithelial odontogenic tumor (CEOT) is a rarely reported benign tumor, accounting for 0.4-3% of all odontogenic tumors. Approximately 150 cases have been reported in the literature between 1958 and 2003. The age range of CEOT varies from 8 to 92 years with mean of 36.9 years, and the occurrence of the lesion in both genders is almost equal. It has 2 clinico-topographic variants: the intraosseous (94%) and the extraosseous (6%) type. The intraosseous type has a predilection for mandible (maxilla : mandible ratio of 1 : 2). The intraosseous CEOT commonly associated with non-erupted teeth accounts for more than half (52%) of the cases and usually appears as painless swelling that causes bony expansion. The location of diffused round-shaped calcifying material is inside the connective tissue stroma and epithelial islands. The tumors tend to be located toward the tooth crown, which usually has a unilocular radiolucent region containing variant radiopaque materials radiologically. In this paper, we report a case of CEOT occurring in the left mandibular first premolar of a 23-year-old female and present a brief review of the literature.

Keyword

Calcifying epithelial odontogenic tumor

MeSH Terms

Accounting
Bicuspid
Connective Tissue
Female
Humans
Islands
Mandible
Odontogenic Tumors
Skin Neoplasms
Tooth
Tooth Crown
Young Adult
Odontogenic Tumors
Skin Neoplasms

Figure

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  Fig. 1 The radiolucent mass contains some agglomerated radiopaque materials around the impacted left mandibular first premolar (A) and Dental CT view (sagittal view) (B). The mandibular canal passes just beneath the mass.

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  Fig. 2 The lesion does not appear as bony perforation but slightly bony expansion (A), and the crown is exposed (B). Calcifying materials are scattered on the inner side of mass (C) and after tibial bone graft (D).

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  Fig. 3 Post-operative panoramic radiography.

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  Fig. 4 Deep-stained calcifying materials and eosinophilic amyloids. The epithelial cells shaped like strands surround the calcifying materials. The amyloids show red color in Congo red staining and bright apple green color- which means bi-refringence-in polarizing microscopic view. A. Optical microscopic view (H&E staining, ×40). B. Optical microscopic view (H&E staining, ×200). C. Optical microscopic view (Congo red staining, ×200). D. Polarizing microscopic view (Congo red staining, ×200).

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  Fig. 5 Post-operative 10-month panoramic radiography.

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