Korean J Otolaryngol-Head Neck Surg.  2005 Feb;48(2):182-188.

Histological Evaluation of Gore-Tex(R) used in Nasal Augmentation of Human

• Park CH
• Kim DY
• Chu HR
• Chun JH
• Choi YH
• Huh WS
• Moon HJ
• Jung DH

Abstract

BACKGROUND AND OBJECTIVES
Although Gore-Tex is popularly used in nasal augmentation in human, studies about the histological changes have been carried out only in animal models. The purpose of this study is to investigate histological changes of Gore-Tex used in nasal augmentation in human. SUBJECTS AND METHODS: Gore-Tex of 24 patients who underwent nasal augmentation using Gore-Tex (non-reinforced sheets) 2-36 months ago and had re-operated for the sole cosmetic problems was obtained. Histologic examination was performed from specimens including Gore-Tex and the surrounding soft tissue with light microscope and electromicroscope. RESULTS: Histologically, connective tissue ingrowth was observed in all specimen. But the degree of foreign body reaction and collagen deposit varied from specimen to specimen and had no relationship with the duration. Neovascularization was observed from specimen whose duration was longer than 12 months and degenerative calcification was observed from 36 month old specimen. CONCLUSION: Unlike the findings of previous reports, individual differences and partial degenerative lesions in Gore-Tex were observed. Additional studies are required to confirm the stability of Gore-Tex as an implant to be used in human.

Keyword

Rhinoplasty; Polytetrafluoroethylene; Histology

MeSH Terms

Child, Preschool
Collagen
Connective Tissue
Foreign-Body Reaction
Humans*
Individuality
Models, Animal
Polytetrafluoroethylene
Rhinoplasty
Collagen
Polytetrafluoroethylene