Korean J Occup Environ Med.
2007 Dec;19(4):268-275.
Mercury Concentrations of Maternal and Umbilical Cord Blood in Korean Pregnant Women: Preliminary Study
- Affiliations
-
- 1Department of Preventive Medicine, College of Medicine, Dong-A University, Korea. yshong@dau.ac.kr
- 2Ministry of Environment, National Institute of Environmental Research (NER), Seoul, Korea. kimds4@me.go.kr
- 3Department of Obstetrics and Gynecology, College of Medicine, Dong-A University, Korea.
- 4Department of Preventive Medicine, College of Medicine, Kosin University, Korea.
- 5Department of Occupational Medicine, Masan Samsung Hospital, Korea.
- 6Department of Pathology, College of Medicine, Dong-A University, Korea.
- 7Department of Occupational Medicine, Dong-A University Hospital, Korea.
- 8Department of Medical Research Center for Cancer Molecular Therapy, Dong-A University, Korea.
Abstract
OBJECTIVES
To evaluate the level of maternal and prenatal mercury exposure and to analyze the related factors.
METHODS
Fifty-nine pregnant women were recruited into this study after obtaining informed consent. Samples were collected at delivery from normal pregnant women who were living in the city of Busan, Korea. Mercury concentrations in maternal and umbilical cord blood samples were measured using a gold-amalgam collection method. The total and methyl mercury levels of 36 of the 59 pregnant women were analyzed after randomization, and the results were compared.
RESULTS
The mean total mercury concentration was 3.16+/-1.21 ppb and 5.43+/-2.22 ppb in maternal and cord blood, respectively. The average, maternal blood mercury level was lower than the prescribed toxic limit for human (WHO, 5 ppb), whereas the cord blood mercury was higher. The mercury exposure level exceeded the WHO recommendation in 5 (8.47%) cases of maternal blood and 29 of (49.15%) cord blood. There was a significant correlation between maternal and cord blood mercury concentrations. Total mercury and methyl mercury concentrations of the 36 random pregnant women were 3.06+/-1.17 ppb, and 2.60+/-1.11 ppb in maternal blood, and 5.20+/-2.36 ppb, and 4.70+/-1.97 ppb in cord blood, respectively. Methyl mercury accounted for 85.0% of the total mercury in maternal blood and 90.4% in cord blood. There was a significant correlation between total and methyl mercury concentrations.
CONCLUSIONS
The study results suggest that mercury concentrations of cord blood may be regarded as indicative of high prenatal mercury exposure. Therefore, further studies are necessary to explain the cause of high mercury concentrations in cord blood, and to examine its relationship with various health indices.
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