Korean J Gastrointest Endosc.  2001 Mar;22(3):164-168.

A Case of Menetrier's Disease

Affiliations
  • 1Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
  • 2Department of Pathology, Wonkwang University College of Medicine, Iksan, Korea.

Abstract

Menetrier's disease is a form of hypertrophic gastropathy occurring primarily in middle-aged males. Patients generally present clinically with dyspepsia and, on occasion, with hypoproteinemic edema and anemia. The latter feature, when combined with the radiographic appearance of the stomach in Menetrier's disease, can lend to confusion with carcinoma and malignant lymphoma. A 45-year-old male was admitted with chief complaint of epigastric dscomfort. Endoscopic examination revealed the appearance of enlarged gastric folds involving the body and fundus of the stomach with relative sparing of the antrum and endoscopic ultrasonography (EUS) reveals characteristic thickening with enhanced echogenicity of the second layer. Biopsies revealed foveolar hyperplasia with cystic dilatation of the glands, compatible with Menetrier's disease. We report a case of Menetrier's disease with brief review of literatures.

Keyword

Menetrier's disease

MeSH Terms

Anemia
Biopsy
Dilatation
Dyspepsia
Edema
Endosonography
Gastritis, Hypertrophic*
Humans
Hyperplasia
Lymphoma
Male
Middle Aged
Stomach
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