Korean J Pathol.  1999 Jul;33(7):525-528.

Prostatic Tissue in Ovarian Mature Cystic Teratoma: A case report

• Hong SM
• Choe MS
• Han EM
• Lee HK
• Ro JY

Abstract

Ovarian mature cystic teratoma containing benign prostatic tissue is rare and only 11 cases have been reported in the literature to date. We report a case of mature cystic teratoma of the ovary containing prostatic tissue. A 23-year-old female patient came to our hospital complaining of irregular menstruation for 3 months. Her menarche had occurred when she was 13 years old. The patient showed no evidence of virilization nor of endocrinopathy. A goose-egg-sized mass was palpable in the left lower abdomen on physical examination. Ultrasonography revealed a cystic ovarian mass with internal echogenecity. Microscopic finding was consistent with that of usual mature cystic teratoma except for a 1.5 cm focus of prostatic and bladder tissues. Prostatic tissue demonstrated strong immunoreactivity for prostatic specific antigen (PSA), prostatic alkaline phosphatase (PAP) and cytokeratin 7. Basal cells of the prostate glands were positive for high molecular weight cytokeratin (34betaE12). Although ovarian mature cystic teratoma containing prostatic tissue has been reported as a rare occurrence, a careful examination with immunohistochemical staining may increase the detection of prostatic tissue in mature cystic teratoma of the ovary.

Keyword

Ovarian teratoma; Prostatic tissue

MeSH Terms

Abdomen
Adolescent
Alkaline Phosphatase
Female
Humans
Keratin-7
Keratins
Menarche
Menstruation
Molecular Weight
Ovary
Physical Examination
Prostate
Teratoma*
Ultrasonography
Urinary Bladder
Virilism
Young Adult
Alkaline Phosphatase
Keratin-7
Keratins