J Korean Surg Soc.
2000 May;58(5):740-744.
Hypereosinophilic Syndrome Accompanied by Digital Necrosis
- Affiliations
-
- 1Department of Surgery, College of Medicine, The Catholic University of Korea.
Abstract
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Hypereosinophilic syndrome (HES) is a heterogeneous group of disorders with the common feature
of prolonged eosinophilia of unknown cause and associated dysfunctions of organ systems, including
the hematologic, cardiovascular, cutaneous, neurologic and respiratory systems, as well as the spleen,
liver, eye, and gastrointestinal tract. Bone marrow is involved in almost all subjects, and the most severe
complications involve the heart and the central nervous systems. We report a case of HES observed
in a 37-year-old man with digital necrosis and persistent eosinophilia lasting for more than 6 months.
This patient also showed signs of peripheral neuropathy, cutaneous manifestations, and eosinophilic
hyperplasia on the bone marrow biopsy.