J Korean Soc Plast Reconstr Surg.  2009 Nov;36(6):792-794.

A Case Report of Palatoplasty in a Patient with Clotting Factor X Deficiency

Affiliations
  • 1Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul, Korea. ejeong@kma.org
  • 2Department of Plastic and Reconstructive Surgery, Korea University College of Medicine, Seoul, Korea.
  • 3Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.

Abstract

PURPOSE
Clotting factor X deficiency is one of the least common coagulation disorders. The authors describe a case of cleft palate in a patient with a congenital clotting factor X deficiency.
METHODS
In pediatric patients with a cleft palate, the coagulation problem is more worrisome, because they are more sensitive to blood than adults, and because postoperative bleeding can cause blood ingestion with subsequent vomiting, aspiration, and airway obstruction. To prevent hemorrhagic complications in the described case, fresh frozen plasma (FFP) was administered every 24 hours from the day before surgery to the second postoperative day.
RESULTS
Good hemostasis, normal healing, and no complications was shown postoperatively.
CONCLUSION
The replacement of fresh frozen plasma was useful in the case of congenital clotting factor deficiency for bleeding prophylaxis in cleft palate operation.

Keyword

Cleft palate; Clotting factor X deficiency; Bleeding prophylaxis

MeSH Terms

Adult
Airway Obstruction
Cleft Palate
Eating
Factor X
Factor X Deficiency
Hemorrhage
Hemostasis
Humans
Plasma
Vomiting
Factor X
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