Korean J Reprod Med.  2007 Sep;34(3):173-178.

The Clinical Outcome of Twin Pregnancies after IVF

Affiliations
  • 1Dong-A University Department of Obstetrics and Gynecology. hmsobgy@dau.ac.kr

Abstract


OBJECTIVE
To compare the outcome of twin pregnancies after in-vitro fertilization (IVF) with that of spontaneously conceived twins.
METHODS
We analyzed 146 twins retrospectively, who had been delivered between January 2000 and July 2005. After reviewing their obstetric medical records, 72 twins conceived with IVF (IVF group) and 51 spontaneously conceived twins (spontaneous group), whose gestational age was over 24 weeks, were recruited for this study.
RESULTS
There were no significant statistical differences of demographic features such as maternal age, gestational age and fetal weight between the two groups. However, the risk of pregnancy-induced hypertension (PIH) and gestational diabetes (G-DM) had significantly increased in the group of IVF (OR 2.59; 95% CI 1.01~6.66). The risk of fetal weight discordancy rate (>20%) and fetal-sex homology rate in IVF group were decreased (OR 0.37; 95% CI 0.14~0.96, OR 0.45; 95% CI 0.21~0.99).
CONCLUSION
In this comparative study, maternal PIH and G-DM risks of IVF group are higher than that of spontaneous group. But, fetal-weight discordancy risk and fetal-sex homology rate were lower in IVF group.

Keyword

Twin; In vitro fertilization; Pregnancy outcome

MeSH Terms

Diabetes, Gestational
Female
Fertilization
Fertilization in Vitro
Fetal Weight
Gestational Age
Humans
Hypertension, Pregnancy-Induced
Maternal Age
Medical Records
Pregnancy
Pregnancy Outcome
Pregnancy, Twin*
Retrospective Studies
Twins*
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