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New Insights on the Mechanisms Affecting Fertility in Men with Non-Seminoma Testicular Cancer before Cancer Therapy

Dias TR, Agarwal A, Pushparaj , Ahmad G, Sharma R

PURPOSE: Patients with non-seminoma testicular cancer (NSTC) cancer can be subfertile or infertile, and present reduced sperm quality, but the underlying mechanisms are unknown. The aim of this study was...
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Association between in vitro fertilization success rate and ambient air pollution: a possible explanation of within-year variation of in vitro fertilization success rate

Kang J, Lee JY, Song H, Shin SJ, Kim J

OBJECTIVE: To evaluate patterns in air pollution concentrations and in vitro fertilization (IVF) success rates using data from a large, long-term clinical database. METHODS: We conducted a retrospective cohort study investigating...
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Induction of cell deathin early developmental phase of zebrafish treated with diethylnitrosamine

Kang JS

The purpose of this study was to investigate diethylnitrosamine (DEN)-induced liver damage in zebrafish. Zebrafish larvae were divided into five groups after seventy-two hours fertilization: group 1 (G1) as control,...
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Successful in vitro fertilization pregnancy and delivery after a fertility-sparing laparoscopic operation in a patient with a papillary thyroid carcinoma arising from a mature cystic teratoma

Hong K, Han AK, Kim ML, Yun BS, Jun HS, Seong SJ, Shim JY

Malignant transformation of ovarian mature cystic teratomas is rare, and papillary thyroid cancer occurs in 0.1%–0.3% of ovarian teratomas that undergo malignant transformation. We describe a case of successful in...
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Male Inflammatory Parameters Are not Useful to Predict the Outcomes of Intracytoplasmic Sperm Injection: Results from a Cross-Sectional Study

Cito G, Coccia ME, Picone R, Cocci A, Russo GI, Cai T, Bencini G, Fucci R, Micelli E, Criscuoli , Bertocci F, Borrani E, Serni S, Carini M, Natali A

PURPOSE: The relationship between male systemic inflammation and fertility seems intriguing, but no data about its impact on the assisted reproductive technology outcomes has been reported. Here, we aimed to...
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Awareness and Usage Patterns of Housewives in Busan for Consuming Marine Products

Lee JS

We conducted this study to compare the awareness and attitude of Busan housewives about consuming marine products. The survey was conducted from April 10 to May 31, 2019 by using...
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Pathogenetic factors involved in recurrent pregnancy loss from multiple aspects

Pei CZ, Kim YJ, Baek KH

Recurrent pregnancy loss (RPL) is a common complication in obstetrics, affecting about 5% of women of childbearing age. An increase in the number of abortions results in escalation in the...
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Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males

Dahril , Aulanni'am , Keumala V, Mustafa A

PURPOSE: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the...
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Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice

Lee J, Lee HC, Kim SY, Cho GJ, Woodruff T

PURPOSE: The aim of this study was to investigate how type I diabetes mellitus (T1D) affects the folliculogenesis and oocyte development, fertilization, and embryo development. MATERIALS AND METHODS: A comparative animal...
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Efficacy and fertility outcomes of levonorgestrel-releasing intra-uterine system treatment for patients with atypical complex hyperplasia or endometrial cancer: a retrospective study

Leone Roberti Maggiore U, Martinelli F, Dondi G, Bogani G, Chiappa V, Evangelista MT, Liberale V, Ditto A, Ferrero S, Raspagliesi F

OBJECTIVE: To investigate the efficacy of levonorgestrel-releasing intra-uterine system (LNG-IUS) treatment in patients affected by atypical complex hyperplasia/endometrial cancer (ACH/EC) wishing to preserve their fertility and to present fertility outcomes...
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Perinatal Outcomes of In Vitro Fertilization Versus Natural Pregnancy in Very Low Birth Weight Infants

Baek KS, Han S, Kim OH, Heo JS, Jeon J

OBJECTIVE: In vitro fertilization (IVF) pregnancy is increasing. The recent reviews have reported the perinatal outcomes of IVF were preterm birth, low birth weight, small for gestational age, congenital malformations,...
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Clinical application of serum anti-Müllerian hormone in women

Oh SR, Choe SY, Cho YJ

Anti-Müllerian hormone (AMH), a peptide growth factor of the transforming growth factor-β family, is a reliable marker of ovarian reserve. Regarding assisted reproductive technology, AMH has been efficiently used as...
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Effect of Sperm DNA Fragmentation on Embryo Quality in Normal Responder Women in In Vitro Fertilization and Intracytoplasmic Sperm Injection

Kim SM, Kim SK, Jee BC, Kim SH

PURPOSE: To investigate the associations between sperm DNA fragmentation (SDF) and embryo formation rate in normal responder women to in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). MATERIALS AND METHODS: Fifty-three consecutive, fresh...
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Traditional Chinese Medicine as a Remedy for Male Infertility: A Review

Zhou SH, Deng YF, Weng ZW, Weng HW, Liu ZD

Male infertility (MI) is a complex multifactorial disease, and idiopathic infertility accounts for 30% of cases of MI. At present, the evidence for the effectiveness of empirical drugs is limited,...
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Epigenetics of Male Fertility: Effects on Assisted Reproductive Techniques

Giacone F, Cannarella R, Mongioì L, Alamo A, Condorelli RA, Calogero A, La Vignera S

During the last decades the study of male infertility and the introduction of the assisted reproductive techniques (ARTs) has allowed to understand that normal sperm parameters do not always predict...
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Review of Guidelines for the Evaluation and Treatment of Leukocytospermia in Male Infertility

Brunner RJ, Demeter JH, Sindhwani

Leukocytospermia is an ill-defined and poorly understood condition affecting up to 30% of male factor infertility. Current guidelines on leukocytospermia vary significantly, although it has been linked to increased rates...
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Reproductive counseling and pregnancy outcomes after radical trachelectomy for early stage cervical cancer

Shah JS, Jooya ND, Woodard TL, Ramirez PT, Fleming ND, Frumovitz

OBJECTIVE: To evaluate patient perceptions of preoperative reproductive counseling and to evaluate complications and pregnancy outcomes in women who had radical trachelectomy (RT) for early stage cervical cancer. METHODS: Patients who...
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Characteristics of Caregivers in Disney Animations

Bahn GH, Lee SY, Hong M, Lee YJ

OBJECTIVES: To assess Disney's animated films regarding development of the conception of family for children, we examined types and roles of caregivers in films. METHODS: The subjects were 54 Disney animations,...
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A point of confusion for embryologists in the identification of viable spermatozoa by the eosin-nigrosin test

Chen H, Zhou H, Shu J, Gan X, Wang C, Lin R

A viable spermatozoon is a prerequisite for fertilization in intracytoplasmic sperm injection (ICSI). Thus, it is crucial to select viable but immotile spermatozoa on the day of ICSI. We report...
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Effects of paternal age on human embryo development in in vitro fertilization with preimplantation genetic screening

Kim MK, Park JK, Jeon Y, Seok SH, Chang EM, Lee WS

OBJECTIVE: As paternal age increases, the quality of sperm decreases due to increased DNA fragmentation and aneuploidy. Higher levels of structural chromosomal aberrations in the gametes ultimately decrease both the...
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