Korean J Med.  2004 Feb;66(2):204-208.

A case of Sheehan's syndrome presented by recurrent ventricular tachycardia

Affiliations
  • 1Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea. parkbhmd@wonkwang.ac.kr

Abstract

Electrocardiographic abnormalities commonly associated with hypopituitarism are low QRS voltage, ST-segment depression, inverted T waves and a prolonged QT interval. Although the mechanism remains unclear, glucocorticoid therapy, an intracelluar-extracellular electrolyte imbalance of myocytes, and histopathological changes in the myocardium are thought to play a role in this disorder. We discribe a 64 year old woman with recurrent ventricular tachycardia associated with QT prolongation in Sheehan's syndrome. Ventricualr tachycardia was treated by lidocain and direct current cardioversion. Sheehan's syndrome was confirmed by past history, anterior pituirary stimulation test and brain MRI showed empty sella. After hormone replacement treatment, inverted T waves and prolonged QT interval was normalized and ventricular tachycardia did not recur.

Keyword

Sheehan's syndrome; Ventricular Tachycardia; QT prolongation

MeSH Terms

Brain
Depression
Electric Countershock
Electrocardiography
Female
Humans
Hypopituitarism*
Magnetic Resonance Imaging
Middle Aged
Muscle Cells
Myocardium
Tachycardia
Tachycardia, Ventricular*
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