Korean J Pathol.  2002 Jun;36(3):195-198.

Pleomorphic Hyalinizing Angiectatic Tumor of Soft Parts: A Case Report

• Chu YC
• Choi SK
• Park IS
• Han HS
• Han JY
• Kim JM

Abstract

A case of rare pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts is reported. A 35-year-old woman presented with a subcutaneous solid mass in the left inguinal area, which had been present for 3 months, was presented to us. The tumor was histologically characterized by sheets of mitotically inactive oval and pleomorphic cells, mono-and multinucleated giant cells, intranuclear cytoplasmic inclusions, and prominent clusters of thinwalled ectatic vessels with perivascular hyalinization. A focal hemangiopericytoma-like vascular pattern, pseudovascular spaces, stromal collagen with degenerative change and abundant mast cells were observed. The tumor cells were reactive for vimentin and CD34. This tumor shared several features with malignant fibrous histiocytoma, ancient schwannoma, giant cell angiofibroma, giant cell fibroblastoma and solitary fibrous tumor. The patient was well with no evidence of disease for 10 months.

Keyword

Soft Tissue Neoplasms; Antiqens, CD34

MeSH Terms

Adult
Angiofibroma
Collagen
Female
Giant Cells
Histiocytoma, Malignant Fibrous
Humans
Hyalin*
Inclusion Bodies
Mast Cells
Neurilemmoma
Soft Tissue Neoplasms
Solitary Fibrous Tumors
Vimentin
Collagen
Vimentin