Intest Res.  2010 Jun;8(1):58-62. 10.5217/ir.2010.8.1.58.

Recurrent Primary Signet Ring Cell Cancer of the Colon at Anastomosis Site after Curative Resection

• Suh YJ
• Cha JM
• Lee JI
• Joo KR
• Jung SW
• Shin HP
• Kim SW

• KMID: 1974731
• DOI: http://doi.org/10.5217/ir.2010.8.1.58

Abstract

A primary signet ring cell cancer (SRCC) is a rare form of an adenocarcinoma of the large intestine. The prognosis of SRCC of the colon has been reported to be worse than classic adenocarcinoma of the colon; however, there is no difference in the post-operative surveillance for SRCC. We report a case of SRCC of the colon with negative resection margins that recurred at the anastomosis site 26 months after curative resection. A 55-year-old male presented to the hospital with abdominal pain. The initial colonoscopy and abdominal computed tomography revealed SRCC of the proximal ascending colon. He underwent extensive curative surgical resection and adjuvant chemotherapy for 8 months. However, 26 months post-operatively, the cancer recurred at the anastomosis site without peritoneal dissemination. Physicians should be aware that SRCC may have different recurrence patterns compared with classic adenocarcinoma, and may need more vigorous surveillance, even after curative surgery.

Keyword

Colon; Signet Ring Cell Carcinoma; Recurrence

MeSH Terms

Abdominal Pain
Adenocarcinoma
Carcinoma, Signet Ring Cell
Chemotherapy, Adjuvant
Colon
Colon, Ascending
Colonic Neoplasms
Colonoscopy
Humans
Intestine, Large
Male
Middle Aged
Prognosis
Recurrence