Chonnam Med J.
1996 Jun;32(1):101-106.
A Case Report for Familial Adenomatous Polyposis with Rectal Adenocarcinoma
- Affiliations
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- 1Department of Internal Medicine, Chunnan Hospital, Yosu, Korea.
Abstract
- Familial adenomatous polysis is characterized by an autosomal dominant mode of inheritnace. In this disease, the entire colorectal mucosa is covered by hundred (often innumerable) polyps of various dimensions. In addition, extracolonic abnormalities, mandibular, osteomas, soft tissue tumor and abnormal dentition, have been reported. The diagnosis is made by endoscopy and/or contrast barium enema. Biopsy is essential to verify that the lesions are adenomatous. Because of the almost progression to malignancy, total proctocolectomy and ileostomy definitely eliminate the possibility of colorectal carcinoma. Total abdominal colectomy with ileoproctostomy or rectal mucosectomy and ileoanal pull-through have been alternative approaches. We experienced one case of familial adenomatous polyposis with rectal carcinoma along with a review of literature.
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